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2.3.3.6: 2-ethylmalate synthase

This is an abbreviated version!
For detailed information about 2-ethylmalate synthase, go to the full flat file.

Reaction

acetyl-CoA
+
H2O
+
2-oxobutanoate
=
(R)-2-ethylmalate
+
CoA

Synonyms

(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating), 2-ethylmalate-3-hydroxybutanedioate synthase, EC 4.1.3.33, propylmalate synthase, propylmalic synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.3 Acyl groups converted into alkyl groups on transfer
                2.3.3.6 2-ethylmalate synthase

Reference

Reference on EC 2.3.3.6 - 2-ethylmalate synthase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Strassman, M.; Ceci, L.N.
A study of acetyl-CoA condensation with alpha-keto acids
Arch. Biochem. Biophys.
119
420-428
1967
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Rabin, R.; Salomon, I.I.; Bleiweis, A.S.; Carlin, J.; Ajl, S.J.
Metabolism of ethylmalic acids by Pseudomonas aeruginosa
Biochem. J.
7
377-389
1968
Pseudomonas aeruginosa
Manually annotated by BRENDA team