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2.3.3.5: 2-methylcitrate synthase

This is an abbreviated version!
For detailed information about 2-methylcitrate synthase, go to the full flat file.

Word Map on EC 2.3.3.5

Reaction

propanoyl-CoA
+
H2O
 +
oxaloacetate
=
(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate
 +
CoA

Synonyms

2-MC synthase, 2-MCS, 2-MCS1, 2-methylcitrate oxaloacetate-lyase, 2-methylcitrate synthase 2, citrate synthase II, citrate synthase/2-methylcitrate synthase, EC 4.1.3.31, MCA condensing enzyme, MCS, Mcs1, mcsA, Methylcitrate synthase, methylcitrate synthetase, mmgD, MscA, PrpC, prpC2, Rv1131

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.3 Acyl groups converted into alkyl groups on transfer
                2.3.3.5 2-methylcitrate synthase

Specific Activity

Specific Activity on EC 2.3.3.5 - 2-methylcitrate synthase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.002
-
CBS 1904, CBS 2015
0.003
-
wild-type strain, carbon source glucose
0.004
-
complemented methylcitrate synthase mutant 11/12 B1, carbon source glucose
0.005
-
OM-102
0.0051
-
nuclei-free homogenate, glucose grown cells
0.006
-
CBS 6174
0.007
0.0092
-
nuclei-free homogenate, n-alkane grown cells
0.011
0.012
0.014
0.016
0.018
0.019
-
heavy particulate fraction, glucose grown cells
0.025
-
-
0.027
0.028
-
IFO 1457
0.029
-
complemented methylcitrate synthase mutant 11/12 B1, carbon source olive oil
0.034
-
IFO 1542
0.042
-
CBS 0882
0.052
-
R-2, propionyl-CoA
0.053
Ustilago crus-galli
-
-
0.056
-
CBS 0586
0.085
-
wild-type strain, carbon source peptone
0.12
-
partially purified preparation
0.13
-
strain SMI45
0.165
-
complemented methylcitrate synthase mutant 11/12 B1, carbon source peptone
0.2
-
strain SMB/acuA
0.21
-
IFO 1659, acetyl-CoA
0.22
-
R-2, acetyl-CoA
0.436
-
substrate propionyl-CoA
0.623
-
substrate acetyl-CoA
14.5
-
purified native enzyme, with oxaloacetate and propionyl-CoA
15.31
-
propionyl-CoA
17.7
purified native enzyme, with oxaloacetate and propionyl-CoA
19.05
-
acetyl-CoA
19.55
-
propionyl-CoA
36.6
-
acetyl-CoA
41.5
-
purified native enzyme, with oxaloacetate and acetyl-CoA
48
purified native enzyme, with oxaloacetate and acetyl-CoA