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2.3.3.16: citrate synthase (unknown stereospecificity)

This is an abbreviated version!
For detailed information about citrate synthase (unknown stereospecificity), go to the full flat file.

Word Map on EC 2.3.3.16

Reaction

acetyl-CoA
+
H2O
+
oxaloacetate
=
citrate
+
CoA

Synonyms

bifunctional citrate synthase/2-methylcitrate synthase, CCNA_01983, CIT1, CitA, citrate condensing enzyme, citrate oxaloacetate-lyase (CoA-acetylating), citrate oxaloacetate-lyase, CoA-acetylating, citrate synthase, citrate synthase Cit1, citrate synthase/2-methylcitrate synthase, citrate synthetase, citric synthase, citric-condensing enzyme, citrogenase, CitZ, CS, CS1, CS2, CS3, CS4, CSI, CSY, CSY4, CTS, EC 4.1.3.7, gltA, GltA2, MCS, mitochondrial citrate synthase, mmgD, More, Msed_1522, oxalacetic transacetase, oxaloacetate transacetase, peroxisomal citrate synthase, Rv0896, SbnG, Si-citrate synthase, sll0401, SSO2589, St0589, St1805, synthase, citrate, TTHA1343, type II citrate synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.3 Acyl groups converted into alkyl groups on transfer
                2.3.3.16 citrate synthase (unknown stereospecificity)

Natural Substrates Products

Natural Substrates Products on EC 2.3.3.16 - citrate synthase (unknown stereospecificity)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + H2O + oxaloacetate
citrate + CoA
show the reaction diagram
acetyl-CoA + oxaloacetate + H2O
citrate + CoA
show the reaction diagram
propanoyl-CoA + H2O + oxaloacetate
(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA
show the reaction diagram
bifunctional enzyme with 2.3-fold higher activity as a 2-methylcitrate synthase
-
-
?
propionyl-CoA + H2O + oxaloacetate
(2S,3S)-2-methylcitrate + CoA
show the reaction diagram
MmgD is a bifunctional citrate synthase/2-methylcitrate synthase with 2.3fold higher activity as a 2-methylcitrate synthase. The enzyme is involved in the methylcitric acid cycle
-
-
?
additional information
?
-