2.3.2.B12: ubiquitin transferase U-box E4
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For detailed information about ubiquitin transferase U-box E4, go to the full flat file.
Reaction
Synonyms
CHIP, CYC4, DUF1076 domain-containing protein, E4, E4 factor, E4 ligase, E4 ubiquitin ligase, E4 ubiquitin-protein ligase UFD2, MUSE3, PRP19, StoD, STY1076, Ub-conjugating E4 factor, Ube4A, UBE4B, ubiquitin chain elongation enzyme Ufd2, ubiquitin conjugation factor E4, ubiquitin fusion degradation protein 2, Ubr1-dependent E4 enzyme, UFD-2, Ufd2, Ufd2a, Ufd2b, Ufd4, Ufd4-enhancing ubiquitiylation enzyme
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Engineering
Engineering on EC 2.3.2.B12 - ubiquitin transferase U-box E4
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P1140A
mutation of the conserved proline residue, abolishes E3 activity of isoform UFD2a
additional information
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mutations of MUSE3, muse3-1 and muse3-2 show enhanced resistance against the virulent oomycete Hyaloperonospora arabidopsidis Noco2 or the bacterial pathogen Pseudomonas syringae pv maculicola ES4326
additional information
AI390103
deletion of the U-box domain abolishes E3 activity of isoform UFD2a
additional information
deletion of the U-box domain abolishes E3 activity of isoform UFD2a
additional information
deletion of the U-box domain abolishes E3 activity of isoform UFD2a
additional information
AI390103
isoform CHIP mutants lacking the U box domain fail to exhibit polyubiquitination activity
additional information
isoform CHIP mutants lacking the U box domain fail to exhibit polyubiquitination activity
additional information
isoform CHIP mutants lacking the U box domain fail to exhibit polyubiquitination activity