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2.3.2.6: lysine/arginine leucyltransferase

This is an abbreviated version!
For detailed information about lysine/arginine leucyltransferase, go to the full flat file.

Word Map on EC 2.3.2.6

Reaction

L-leucyl-tRNALeu
+
N-terminal L-arginyl-[protein]
=
tRNALeu
+
N-terminal L-leucyl-L-arginyl-[protein]

Synonyms

AAT, aminoacyl transferase, aminoacyl tRNA protein transferase, L/F transferase, L/F-transferase, L/F-tRNA-protein transferase, leucyl, phenylalanine-tRNA-protein transferase, leucyl, phenylalanyl transfer ribonucleic acid-protein transferase, leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase, leucyl-phenylalanine-transfer ribonucleate-protein transferase, leucyl/phenylalaninyl tRNA protein transferase, leucyl/phenylalanyl tRNA protein transferase, leucyl/phenylalanyl-tRNA protein transferase, leucyl/phenylalanyl-tRNA-protein transferase, leucyltransferase, LF-transferase, LFTR, R/K-transferase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.6 lysine/arginine leucyltransferase

Engineering

Engineering on EC 2.3.2.6 - lysine/arginine leucyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D186A
inactive
D186E
the mutation slightly reduces the reaction rate
D186N
inactive
M144A
the mutant exhibits about 9% activity compared to the wild type
Q188A
the mutant exhibits about 8% activity compared to the wild type
W111A
inactive
W49A
the mutant exhibits about 10% activity compared to the wild type