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2.3.2.27: RING-type E3 ubiquitin transferase

This is an abbreviated version!
For detailed information about RING-type E3 ubiquitin transferase, go to the full flat file.

Word Map on EC 2.3.2.27

Reaction

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine
+
[acceptor protein]-L-lysine
=
[E2 ubiquitin-conjugating enzyme]-L-cysteine
 +
[acceptor protein]-N6-ubiquitinyl-L-lysine

Synonyms

ABA-insensitive RING protein3, abscisic acid-insensitive RING protein 4, ACRE276, AIR1, AIR2, AIRP1, AIRP2, AIRP3, AIRP4, AMFR, Arabidopsis ABA-insensitive RING protein 1, Arabidopsis ABA-insensitive RING protein 2, ARIH1, As-induced RING E3 ligase 2, At1g54150, At1g74410, At2g15580, At4g23450, At4g26400, ATL2, ATL80, Avr9/Cf-9 rapidly elicited protein 276, BIG BROTHER, BIRC3, BRCA1, BRE1A, BRE1B, breast cancer susceptibility protein 1, breast cancer type 1 susceptibility protein, c-Cbl, C3HC4-RING finger E3 ubiquitin ligase, CaRING1, CHIP, cIAP2, Cop1, COP1 SUPPRESSOR1, CSU1, CUL4, cullin-4, DAF, DEAR1, DEFECTIVE IN ANTHER DEHISCENCE1 (DAD1)-activating factor, Der3, Dir1, E3 ligase, E3 ubiquitin ligase, E3 ubiquitin ligase Erysiphe necator-induced RING finger protein 1, E3 ubiquitin ligase RING1, E3 ubiquitin-protein ligase Arkadia, E3 ubiquitin-protein ligase Mdm2, E3 ubiquitin-protein ligase MIR1, E3 ubiquitin-protein ligase RNF25, E3-enzyme, EIRP1, EMR, ERAD-associated E3 ubiquitin-protein ligase DOA10, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-mediating RING finger protein, FANCL, gamma rays-induced RING finger protein1, GIRP1, gp78, H2-10, HCI1, HHARI, HIR1, HOS1, HSPC238, HTAS, HUB1, Human Homologue of Drosophila Ariadne, IDF1, IRT1 degradation factor1, KEEP ON GOING, KEG, Kf-1, LOG2, mahogunin ring finger-1, MARCH10, MARCH6, Mdm2, MEX3C, MGRN1, microtubule-associated E3 ubiquitin ligase isoform 1, MIEL1, MUL1, NERF, NFYA5 enhancing RING FINGER, Os05g41795, Os10g30850, Parkin, Parkinson juvenile disease protein 2, PIR1, PIR2, Pirh2, PLANT U-BOX17, PP2CA interacting RING finger protein 1, PP2CA interacting RING finger protein 2, pre-mRNA-splicing factor 19, PRP19, PUB17, PUB54, RanBP-type and C3HC4-type zinc finger-containing protein 1, RBCK1, RBX1, RCHY1, RFP1, RFPH2-10, RGLG2, RHA2b, Rines, Ring, RING E3, RING E3 ubiquitin ligase, ring finger protein 103, Ring finger protein 186, RING finger ubiquitin E3 ligase, RING-CH 10, ring-finer protein 55, RING-finger E3 ligase, RING-finger E3 ubiquitin ligase, RING-finger ubiquitin ligase Ubr1, RING-H2 finger E3 ubiquitin ligase, RING-H2 finger protein ATL63, RING-IBR-RING ubiquitin ligase, RING-type E3 ligase, RING-type E3 ubiquitin ligase, Ring1B, RMA1, RMA2, RMA3, RN181, RNF103, RNF111, RNF180, RNF186, RNF190, RNF2, RNF20, RNF220, RNF4, RNF43, RNF45, RNF8, salt tolerance RING finger 1, SDIR1, SIRP2, Sis3, SSM4, STIP1 homology and U-Box containing protein 1, Strf1, TEB4, TRIM22, Trim23, TRIM25, TRIM3, TRIM5, TRIM5alpha, TRIM62, TRIM69, tripartite motif-containing protein 5, U-box domain-containing protein 17, Ube4A, UBE4B, ubiquitin ligase E3, ubiquitin ligase Ubr1, ubiquitin-protein ligase K3, UBR1, UFD-2, Xbat32, ZNRF1

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.27 RING-type E3 ubiquitin transferase

Expression

Expression on EC 2.3.2.27 - RING-type E3 ubiquitin transferase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
AIR1 expression is induced under abiotic stress conditions, including drought, salt, heat, and As exposure
-
EMR is significantly upregulated under endoplasmic reticulum stress conditions
enzyme expression is induced by powdery mildew
-
expression is highly induced by heat and cold
expression is induced by avirulent Xanthomonas campestris pv vesicatoria infection
expression is induced by drought
expression is induced by drought stress
expression is induced by salt, drought, heat, and abscisic acid exposure
-
expression is markedly induced by abscisic acid and dehydration stress
-
expression is repressed by low temperature
expression is significantly induced by abscisic acid and drought stress
expression is suppressed by abscisic acid
expression is up-regulated by gamma rays irradiation
-
expression is upregulated by salt, drought and osmotic stresses
expression of AIR2 is induced under various abiotic stress conditions, including heat, salt, drought and As exposure
-
expression of isoform ACRE276 is transiently induced in wounded leaves within 15 min, but upon Avr9 elicitor treatment, this upregulation is enhanced and maintained until cell death onset
expression of RFP1 is induced by protein betaC1 from Tomato yellow leaf curl China virus-associated betasatellite
human melanoma cells express four MGRN isoforms
Rha2b expression is induced by abscisic acid and drought stress
TEB4 expression does not increase in response to the various stress conditions
the enzyme expression is induced strongly (22fold) by 0.1 mM abscisic acid after 12 h. The enzyme is slightly induced (2-4fold) by heat (45°C), cold (4°C), NaCl (250 mM), PEG (20% (w/v)), and H2O2 (100 mM) treatments
-
the enzyme is upregulated by 10 days low phosphate (0-02 mM KH2PO4) conditions
the gene encoding RNF43 is upregulated in colon adenocarcinoma as well as in colon adenoma
the transcription level can be induced by absisic acid (0.1 mM), heat (37°C), osmotic (300 mM mannitol) and oxidative stresses (20 mM H2O2)
-
trancription is downregulated by cold and drought treatments
trancription is upregulated by abscisic acid and salt stress
transcript levels of AIRP3 are up-regulated by drought, high salinity, and abscisic acid