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2.3.1.B40: caliceamicin octaketide synthase

This is an abbreviated version!
For detailed information about caliceamicin octaketide synthase, go to the full flat file.

Word Map on EC 2.3.1.B40

Reaction

8 malonyl-CoA +

NADPH
+
H+
= 8 CoA +
(4E,6E,8E,10E,12E,14E)-3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoic acid
+ 8 CO2 +
NADP+
+
H2O

Synonyms

CalE8, enediyne polyketide synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.B40 caliceamicin octaketide synthase

General Information

General Information on EC 2.3.1.B40 - caliceamicin octaketide synthase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
polyketide is an authentic product of CalE8 and may be a key precursor to the enediyne core of calicheamicin