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2.3.1.B25: octaketide synthase

This is an abbreviated version!
For detailed information about octaketide synthase, go to the full flat file.

Word Map on EC 2.3.1.B25

Reaction

16 malonyl-CoA + 28 H+ = 16 CoA +

2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-2-methyl-2,3-dihydro-4H-chromen-4-one
+
2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-5-methyl-2,3-dihydro-4H-chromen-4-one
+ 16 CO2 + 16 H2O

Synonyms

AaOKS, DynE8, enediyne PKS, enediyne polyketide synthase, OKS, oktaketide synthase, PksE, plant type III OKS, plant type III polyketide synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.B25 octaketide synthase

Reaction

Reaction on EC 2.3.1.B25 - octaketide synthase

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
16 malonyl-CoA + 28 H+ = 16 CoA + 2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-2-methyl-2,3-dihydro-4H-chromen-4-one + 2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-5-methyl-2,3-dihydro-4H-chromen-4-one + 16 CO2 + 16 H2O
show the reaction diagram
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