2.3.1.B25: octaketide synthase

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For detailed information about octaketide synthase, go to the full flat file.

Word Map on EC 2.3.1.B25

2.3.1.B25

plant-specific

aloe

arborescens

condensations

pentaketide

chromone

anthraquinone

dynemicins

micromonospora

10-membered

benzophenone

calicheamicin

hexaketide

precursor-directed

anthrone

naphthopyrone

benzalacetone

nonaketide

n-methylanthraniloyl-coa

acridone

spring-8

palmatum

tetraketides

neocarzinostatin

synthesis

molecular biology

Reaction

16 malonyl-CoA + 28 H+ = 16 CoA +

2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-2-methyl-2,3-dihydro-4H-chromen-4-one

2,7-dihydroxy-5-[(4-hydroxy-2-oxo-2H-pyran-6-yl)methyl]-5-methyl-2,3-dihydro-4H-chromen-4-one

+ 16 CO2 + 16 H2O

Synonyms

AaOKS, DynE8, enediyne PKS, enediyne polyketide synthase, OKS, oktaketide synthase, PksE, plant type III OKS, plant type III polyketide synthase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.B25 octaketide synthase

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Results	in table
2	AA Sequence
3	Application
4	Cloned(Commentary)
1	Expression
13	General Information
1	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
7	Organism
15	Protein Variants
1	Reaction
7	Reference
1	Source Tissue
12	Substrates and Products (Substrate)
1	Subunits
18	Synonyms
1	Systematic Name

Expression

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Expression on EC 2.3.1.B25 - octaketide synthase

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treatment with salicylic acid leads to increased expression of octaketide synthase genes and decreases in malonyl-CoA, with concomitant accumulation of Aloe emodin and chrysophanol

Aloe vera

737124