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2.3.1.94: 6-deoxyerythronolide-B synthase

This is an abbreviated version!
For detailed information about 6-deoxyerythronolide-B synthase, go to the full flat file.

Word Map on EC 2.3.1.94

Reaction

propanoyl-CoA
+ 6 (2S)-methylmalonyl-CoA + 6 NADPH + 6 H+ =
6-Deoxyerythronolide b
 + 7 CoA + 6 CO2 +
H2O
 + 6 NADP+

Synonyms

6-deoxyerythronolide B, 6-deoxyerythronolide B synthase, DEBS, DEBS1, DEBS2, DEBS3, deoxyerythronolide B synthase, deoxyerythronolide B synthase 1, deoxyerythronolide B synthase 2, deoxyerythronolide B synthase 3, eryA, erythromycin polyketide synthase, erythronolide condensing enzyme, erythronolide synthase, PKS, polyketide synthase, synthase, erythronolide

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.94 6-deoxyerythronolide-B synthase

Molecular Weight

Molecular Weight on EC 2.3.1.94 - 6-deoxyerythronolide-B synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10000
-
ACP domain
33000
thioesterase domain, 2 * 33000
37000
-
x * 37000, enzyme may be a component of a multifunctional protein or may exist as a dimer SDS-PAGE
66000
thioesterase domain, homodimer
75000
-
gel filtration
90000
-
crosslinked ketosynthase3-acyltransferase3-ACP3 and ketosynthase5-acyltransferase5-ACP5 domains, determined by SDS-PAGE