2.3.1.80: cysteine-S-conjugate N-acetyltransferase

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For detailed information about cysteine-S-conjugate N-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyltransferase, cysteine S-conjugate N-, NAT8

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.80 cysteine-S-conjugate N-acetyltransferase

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Results	in table
1	Activating Compound
3	AA Sequence
1	Application
1	CAS Registry Number
2	Cloned(Commentary)
6	Inhibitors
17	KM Value [mM]
1	Localization
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
8	Organism
4	Pathway
2	pH Optimum
4	Protein Variants
2	Purification (Commentary)
1	Reaction
1	Reaction Type
8	Reference
8	Source Tissue
1	Specific Activity [micromol/min/mg]
2	Storage Stability
18	Substrates and Products (Substrate)
2	Subunits
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Inhibitors

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Inhibitors on EC 2.3.1.80 - cysteine-S-conjugate N-acetyltransferase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

5,5'-dithiobis-2-nitrobenzoic acid

Homo sapiens

Q9UHE5

strong inhibition

719866

N-ethylmaleimide

Sus scrofa

-

-

487546

octyl glucoside

Homo sapiens

Q9UHE5

10 mM, 80% residual activity. Slight activation at 1 mM

719866

p-chloromercuribenzoate

Sus scrofa

-

-

487546

probenecid

Sus scrofa

-

less pronounced inhibition

487546

additional information

Sus scrofa

-

not inhibitory: PMSF

487546

-