2.3.1.76: retinol O-fatty-acyltransferase

This is an abbreviated version!
For detailed information about retinol O-fatty-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.76

2.3.1.76

esterification

esterify

retinoids

medicine

lecithin:retinol

palmitate

palmitoyl-coa

diacylglycerols

unesterified

3hretinol

hairless

palmitoyl

alumina

chylomicron

all-trans-retinaldehyde

dgats

stearate

11-cis-retinaldehyde

11-cis-retinyl

photobleached

mid-gestation

all-trans-retinyl

Reaction

Synonyms

11-cis-acyl-CoA:retinol O-acyltransferase, 11-cis-ARAT, acyl CoA:retinol acyltransferase, acyl CoA:retinol O-acyltransferase, acyl coenzyme A:retinol acyltransferase, acyl-CoA:retinol acyltransferase, ArAT, DGAT1/ARAT, MFAT, More, multifunctional O-acyltransferase, retinol fatty-acyltransferase, retinyl-ester synthase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.76 retinol O-fatty-acyltransferase

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Results	in table
6	Activating Compound
242	AA Sequence
8	Application
1	CAS Registry Number
6	Cloned(Commentary)
3	Disease/ Diagnostics
1	General Information
2	IC50 Value
20	Inhibitors
3	Ki Value [mM]
12	KM Value [mM]
20	Localization
1	Metals/Ions
26	Natural Substrates/ Products (Substrates)
670	Organism
2	Pathway
4	PDB ID
7	pH Optimum
2	pH Range
10	pH Stability
2	Protein Variants
12	Purification (Commentary)
2	Reaction
1	Reaction Type
22	Reference
37	Source Tissue
17	Specific Activity [micromol/min/mg]
5	Storage Stability
68	Substrates and Products (Substrate)
23	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 2.3.1.76 - retinol O-fatty-acyltransferase

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(6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate

Rattus norvegicus

activity inhibited at 0.5%

487488

2,3,7,8-tetrachlorodibenzo-p-dioxin

Rattus norvegicus

decreased activity

487494

5,5'-dithiobis(2-nitrobenzoic acid)

Rattus norvegicus

activity inhibited above 2 mM

487492

all-trans-retinylbromoacetate

Bos taurus

658662

cellular retinol-binding protein

Rattus norvegicus

specific inhibition of retinol fatty-acyltransferase by capturing substrate

487493

p-chloromercuribenzoate

Rattus norvegicus

activity abolished at 5 mM

487488

p-chloromercuriphenylsulfonic acid

Rattus norvegicus

activity abolished at 6 mM

487492

p-hydroxymercuribenzoate

Rattus norvegicus

activity inhibited at 2 and 6 mM

487492

progesterone

3 entries

sodium deoxycholate

Rattus norvegicus

activity inhibited at 0.5%

487488

sodium taurocholate

Rattus norvegicus

activity abolished at 8 mM

487492

XP620

2 entries

additional information

5 entries