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2.3.1.75: long-chain-alcohol O-fatty-acyltransferase

This is an abbreviated version!
For detailed information about long-chain-alcohol O-fatty-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.75

Reaction

acyl-CoA
+
a long-chain alcohol
=
CoA
+
a long-chain ester

Synonyms

acyl CoA wax alcohol acyltransferase 1, acyl CoA wax alcohol acyltransferase 2, acyl CoA:long-chain fatty alcohol O-acyltransferase, acyl-CoA wax alcohol acyltransferase, acyl-CoA wax alcohol acyltransferase 2, acyl-CoA wax alcohol acyltransferases, acyl-CoA:alcohol transacylase, acyl-CoA:fatty acyl alcohol acyltransferase, acyl-CoA:retinol acyltransferase, acyltransferase, long-chain alcohol, ArAT, ATF, ATF1, AtfA, AtfA1, AtfG25, AWAT, AWAT 1, AWAT 2, AWAT1, AWAT2, bifunctional WS/DGAT, EgWSD2, EgWSD5, fatty acyl-coenzyme A:fatty alcohol acyltransferase, isoprenoid wax ester synthase, Maqu_0168, MFAT, More, multifunctional O-acyltransferase, Rha1, TrWSD4, TrWSD5, unspecific bifunctional wax ester synthase/acyl coenzyme A:diacylglycerol acyltransferase, wax ester synthase, wax ester synthase/acyl CoA:diacylglycerol acyltransferase, wax ester synthase/acyl coenzyme A:diacylglycerol acyltransferase, wax ester synthase/acyl-CoA diacylglycerol acyltransferase, wax ester synthase/acyl-CoA:diacylglycerol acyltransferase, wax ester synthase/acyl-coenzyme A:diacylglycerol acyltransferase, wax ester synthase/diacylglycerol acyltransferase, wax ester synthases/acyl-CoA:diacylglycerol acyltransferase, wax monoester synthase, wax synthase, wax-ester synthase, waxester/diacylglycerol acyltransferase, WE synthase, WE synthases/acyl-CoA:diacylglycerol acyltransferase, WS, WS/DGAT, WS2, WSD1, WSD2, WSD4, WSD5

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.75 long-chain-alcohol O-fatty-acyltransferase

Inhibitors

Inhibitors on EC 2.3.1.75 - long-chain-alcohol O-fatty-acyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
11-cis-retinyl acetate
the presence of 11-cis-retinyl acetate leads to reduction in esterification of 9-cis-retinol
11-cis-retinyl laurate
the presence of 11-cis-retinyl laurate leads to reduction in esterification of 9-cis-retinol
11-cis-retinyl palmitate
the presence of 0.01 mM 11-cis-retinyl palmitate significantly reduces the amount of 9-cis-retinyl ester produced by the enzyme. 11-cis-retinyl palmitate also inhibits13-cis- and all-trans-retinol esterification, but has no effect on formation of 11-cis-retinyl myristate
bovine serum albumin
-
above 5 mg/ml
-
CaCl2
5 mM, 30% inhibition
ethanol
Marinobacter nauticus
substrate inhibition above 0.5 M
MgCl2
5 mM, 17% inhibition
MnCl2
5 mM, 30% inhibition
oleoyl-CoA
substrate inhibition; substrate inhibition
Polyvinylpyrrolidone
-
slight inhibition