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2.3.1.71: glycine N-benzoyltransferase

This is an abbreviated version!
For detailed information about glycine N-benzoyltransferase, go to the full flat file.

Reaction

benzoyl-CoA
+
glycine
=
CoA
 +
hippurate

Synonyms

aralkyl-CoA:glycine N-acyltransferase, benzoyl CoA-amino acid N-acyltransferase, benzoyl-CoA:glycine N-acyltransferase, benzoyltransferase, glycine, GlyAT, glycine N-acyltransferase, GNAT

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.71 glycine N-benzoyltransferase

Engineering

Engineering on EC 2.3.1.71 - glycine N-benzoyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
E226Q
about 3fold increase in Km value for lgycine
E229Q
single nucleotide polymorphism, inactive
F168L
single nucleotide polymorphism, decreased activity compared to wild-type
K16N
single nucleotide polymorphism, enzymic activities similar to wild-type
N156S
single nucleotide polymorphism, more active than wild-type
R131H
single nucleotide polymorphism, enzymic activities similar to wild-type
R199C
single nucleotide polymorphism, inactive
S17T
single nucleotide polymorphism, enzymic activities similar to wild-type