2.3.1.7: carnitine O-acetyltransferase

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For detailed information about carnitine O-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, acuJ, CarAc, CARAT, carnitine acetyl coenzyme A transferase, carnitine acetyl transferase, carnitine acetylase, carnitine acetyltransferase, carnitine acetyltransferase CAT2, carnitine acetyltransferase Cat2p, carnitine acetyltransferase Yat1p, carnitine acetyltransferase Yat2p, carnitine-acetyl-CoA transferase, CAT, CAT2, CATC, CRAT, CT-CAT, CTN1, CTN2, CTN3, H-CAT, P-CAT, S-CAT1, S-CAT2, Yat1

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.7 carnitine O-acetyltransferase

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Results	in table
6	Activating Compound
126	AA Sequence
12	Application
1	CAS Registry Number
19	Cloned(Commentary)
11	Crystallization (Commentary)
173	Disease/ Diagnostics
3	Expression
10	General Information
6	General Stability
3	IC50 Value
116	Inhibitors
37	Ki Value [mM]
188	KM Value [mM]
183	Localization
73	Molecular Weight [Da]
480	Natural Substrates/ Products (Substrates)
563	Organism
11	PDB ID
16	pH Optimum
6	pH Range
2	pH Stability
1	Posttranslational Modification
23	Protein Variants
57	Purification (Commentary)
5	Reaction
1	Reaction Type
156	Reference
233	Source Tissue
30	Specific Activity [micromol/min/mg]
12	Storage Stability
952	Substrates and Products (Substrate)
46	Subunits
97	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
24	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 2.3.1.7 - carnitine O-acetyltransferase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

37 - 50

Rattus norvegicus

-

enzyme retains total activity when kept at 37°C for 30 min, rapid loss of activity above 37°C, loses half of the activity at 40°C for 30 min, but is completely inactivated when kept at 44°C for 30 min or 50°C for 5 min, 75% loss of activity at 37°C for 8 h, only 15% loss when kept at 25°C for 8 h

487403

4

Columba sp.

-

precipitated enzyme is stable at

487397

4 - 25

Rattus norvegicus

-

stored in a refrigerator for 2 days or incubated at 25°C for 5 h, monomeric form remains unchanged

487408