2.3.1.7: carnitine O-acetyltransferase

This is an abbreviated version!
For detailed information about carnitine O-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, acuJ, CarAc, CARAT, carnitine acetyl coenzyme A transferase, carnitine acetyl transferase, carnitine acetylase, carnitine acetyltransferase, carnitine acetyltransferase CAT2, carnitine acetyltransferase Cat2p, carnitine acetyltransferase Yat1p, carnitine acetyltransferase Yat2p, carnitine-acetyl-CoA transferase, CAT, CAT2, CATC, CRAT, CT-CAT, CTN1, CTN2, CTN3, H-CAT, P-CAT, S-CAT1, S-CAT2, Yat1

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.7 carnitine O-acetyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
6	Activating Compound
126	AA Sequence
12	Application
1	CAS Registry Number
19	Cloned(Commentary)
11	Crystallization (Commentary)
173	Disease/ Diagnostics
3	Expression
10	General Information
6	General Stability
3	IC50 Value
116	Inhibitors
37	Ki Value [mM]
188	KM Value [mM]
183	Localization
73	Molecular Weight [Da]
480	Natural Substrates/ Products (Substrates)
563	Organism
11	PDB ID
16	pH Optimum
6	pH Range
2	pH Stability
1	Posttranslational Modification
23	Protein Variants
57	Purification (Commentary)
5	Reaction
1	Reaction Type
156	Reference
233	Source Tissue
30	Specific Activity [micromol/min/mg]
12	Storage Stability
952	Substrates and Products (Substrate)
46	Subunits
97	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
24	Turnover Number [1/s]

Natural Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Natural Substrates Products on EC 2.3.1.7 - carnitine O-acetyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Natural Substrate Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

5 entries

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

19 entries

acetyl-CoA + L-carnitine

CoA + O-acetylcarnitine

Mus musculus

-

-

736560

-

-

?

acyl-CoA + carnitine

acylcarnitine + CoASH

23 entries

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

3 entries

acylcarnitine + CoASH

acyl-CoA + carnitine

23 entries

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

25 entries

additional information

?

-

6 entries

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Homo sapiens

-

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

659194, 660553

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Homo sapiens

P43155

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

659815

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Mus musculus

-

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

657546, 659365, 660553

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Rattus norvegicus

Q704S8

modulates acetyl-CoA and CoA availability for a wide range of acyl-transfer reactions, involved in fatty acid metabolism

659372

-

-

r

acetyl-CoA + carnitine

CoA + O-acetylcarnitine

Saccharomyces cerevisiae

P32796

this reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell

673746

-

-

?

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Aspergillus niger

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Candida albicans

-

-

487427

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Cavia porcellus

-

-

487400, 487404

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Cyberlindnera jadinii

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Lipomyces starkeyi

-

-

487424

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Mus musculus

P47934

-

487428

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Mus musculus

P47934

-

487433

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Ovis aries

-

-

487397, 487400, 487407

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

acetyl-CoA + carnitine

O-acetylcarnitine + CoASH

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Aspergillus niger

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Candida albicans

-

-

487427

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Cavia porcellus

-

-

487400, 487404

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Cyberlindnera jadinii

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Lipomyces starkeyi

-

-

487424

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus

P47934

-

487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus

P47934

-

487433

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus BALB/c

-

-

487420

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Ovis aries

-

-

487397, 487400, 487407

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487417, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

acyl-CoA + carnitine

acylcarnitine + CoASH

Torulopsis bovina

-

-

486295, 487418

-

-

r

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

Homo sapiens

-

-

735903, 736268

-

-

?

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

Mus musculus

-

-

735852

-

-

?

acyl-CoA + L-carnitine

CoA + O-acylcarnitine

Mus musculus

-

-

735906

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Aspergillus niger

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Bos taurus

-

-

486295, 487400, 487404, 487407, 487418, 487423, 487424, 487429

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Candida albicans

-

-

487427

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Cavia porcellus

-

-

487400, 487404

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Cyberlindnera jadinii

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Lipomyces starkeyi

-

-

487424

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus

P47934

-

487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus

P47934

-

487433

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus BALB/c

-

-

487420

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Ovis aries

-

-

487397, 487400, 487407

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487417, 487418, 487421, 487422, 487423, 487424, 487429, 487430, 487432

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Saccharomyces cerevisiae

-

-

487418, 487421, 487424, 487425, 487426, 487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

acylcarnitine + CoASH

acyl-CoA + carnitine

Torulopsis bovina

-

-

486295, 487418

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Aspergillus niger

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Bos taurus

-

-

486295, 487400, 487404, 487418, 487423, 487424, 487429

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Bos taurus

-

mitochondrial fatty acid transport

487407

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Camelus dromedarius

-

-

487421, 487422, 487423

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Candida albicans

-

key enzyme for the translocation of acetyl units between intracellular compartments

487427

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Candida tropicalis

-

-

487402, 487405, 487406, 487410, 487411, 487413, 487415, 487418, 487424, 487425, 487426, 487427

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Cavia porcellus

-

-

487400, 487404

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Columba sp.

-

-

487397, 487399, 487400, 487401, 487403, 487404, 487405, 487406, 487407, 487408, 487410, 487412, 487414, 487418, 487419, 487421, 487422, 487423, 487424, 487426, 487428, 487431, 487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Cutaneotrichosporon curvatum

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Cyberlindnera jadinii

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Homo sapiens

-

-

487399, 487416, 487418, 487421, 487422, 487423, 487424, 487426, 487427, 487428, 487430, 487431, 487433

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Lipomyces starkeyi

-

-

487424

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus

-

-

486295, 487413, 487420, 487421, 487422, 487423, 487424, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus

P47934

-

487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus

P47934

-

487433

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus BALB/c

-

-

487420

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Mus musculus S3T3(ATCC CCL-92)

-

-

487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Oryctolagus cuniculus

-

-

487399, 487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Ovis aries

-

-

487397, 487400, 487407

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Rattus norvegicus

-

-

486295, 487403, 487404, 487406, 487407, 487408, 487410, 487414, 487416, 487418, 487421, 487422, 487423, 487424, 487429, 487430

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Rattus norvegicus

-

key mitochondrial enzyme for fuel utilization, essential functions are to regenerate CoA, which allows peroxisomal beta-oxidation to proceed, and to facilitate transport of acetyl moieties to mitochondria for oxidation

487432

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Rattus norvegicus Sprague-Dawley

-

-

487429

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Saccharomyces cerevisiae

-

-

487421, 487424, 487425, 487426, 487428

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Saccharomyces cerevisiae

-

acetate metabolism, enzyme transports activated acetyl group from the cytosol into the mitochondrial matrix

487418

-

-

r

O-acetylcarnitine + CoASH

acetyl-CoA + carnitine

Sus scrofa

-

-

487397, 487398, 487403, 487404, 487406, 487416, 487422, 487424, 487428

-

-

r

additional information

?

-

Candida albicans

-

carnitine acetyltransferases are required for growth on non-fermentable carbon sources but not for pathogenesis in Candida albicans

688876

-

-

?

additional information

?

-

Candida albicans

-

carnitine acetyltransferases are required for growth on non-fermentable carbon sources but not for pathogenesis in Candida albicans. Strains lacking CTN1 or CTN2 are unable to grow on ethanol or acetate as sole carbon source

688876

-

-

?

additional information

?

-

Saccharomyces cerevisiae

-

carnitine acetyltransferases catalyse the reversible reaction between carnitine and acetyl-CoA to form acetylcarnitine and free CoA. This reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell

673746

-

-

?

additional information

?

-

Saccharomyces cerevisiae

P32796

carnitine acetyltransferases catalyse the reversible reaction between carnitine and acetyl-CoA to form acetylcarnitine and free CoA. This reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell

673746

-

-

?

additional information

?

-

Saccharomyces cerevisiae

-

CAT2 contributes to the response to oxidative stress

686262

-

-

?

additional information

?

-

Saccharomyces cerevisiae

P32796

CAT2 contributes to the response to oxidative stress

686262

-

-

?