2.3.1.60: gentamicin 3-N-acetyltransferase

This is an abbreviated version!
For detailed information about gentamicin 3-N-acetyltransferase, go to the full flat file.

Reaction

Synonyms

3-N-aminoglycoside acetyltransferase, AAC, AAC(3)-I, aac(3)-Ia, AAC(3)-Ib, AAC(3)-IV, aacC1, acetyltransferase, gentamicin 3-, aminoglycoside 3-Nacetyltransferase I, aminoglycoside acetyltransferase, aminoglycoside acetyltransferase AAC(3)-1, aminoglycoside N-acetyltransferase, gentamicin acetyltransferase I, meta-AAC0005, meta-AAC0007, meta-AAC0012, More

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.60 gentamicin 3-N-acetyltransferase

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Results	in table
1	Activating Compound
51	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
2	Crystallization (Commentary)
5	General Information
1	General Stability
16	Inhibitors
11	Ki Value [mM]
3	KM Value [mM]
2	Localization
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
21	Organism
1	pH Optimum
1	pH Range
2	pH Stability
3	Purification (Commentary)
1	Reaction
1	Reaction Type
10	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
3	Storage Stability
38	Substrates and Products (Substrate)
2	Subunits
25	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.1.60 - gentamicin 3-N-acetyltransferase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

acetyl-CoA + astromicin

CoA + N3-acetylastromicin

Pseudomonas aeruginosa

-

-

756303

-

-

?

acetyl-CoA + gentamicin

CoA + N3-acetylgentamicin

Pseudomonas aeruginosa

-

-

756303

-

-

?

acetyl-CoA + sisomicin

CoA + N3-acetylsisomicin

Pseudomonas aeruginosa

-

-

756303

-

-

?

additional information

?

-

Acinetobacter baumannii

O05286

determination of imipenem, meropenem, and gentamicin resistant clinical isolates

736260

-

-

?