2.3.1.57: diamine N-acetyltransferase This is an abbreviated version! For detailed information about diamine N-acetyltransferase, go to the full flat file .
Reaction
acetyl-CoA +
an alkane-alpha,omega-diamine =
CoA +
an N-acetyldiamine
Synonyms acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase, acetyltransferase, putrescine, bltD, CpSSAT, diamine acetyltransferase, More, N1-SAT, N1-spermidine/spermine acetyltransferase, N1SSAT, PaiA, putrescine (diamine)-acetylating enzyme, putrescine acetylase, putrescine acetyltransferase, putrescine N-acetyltransferase, SAT, SAT1, SpeG, spermidine /spermine N1-acetyltransferase, spermidine acetyltransferase, spermidine N-acetyltransferase, spermidine N1-acetyltransferase, spermidine-spermine acetyltransferase, spermidine-spermine N1-acetyltransferase, spermidine/spermine acetyltransferase, spermidine/spermine N-acetyltransferase, spermidine/spermine N1-acetyltransferase, spermidine/spermine N1-acetyltransferase 1, spermidine/spermine N1-acetyltransferase 2, spermidine/spermine N1-acetyltransferase-1, spermidine/spermine-N 1-acetyltransferase, spermidine/spermine-N1-acetyltransferase, spermidine/spermine-N1-acetyltransferase activity, SSAT, SSAT-1, SSAT-2, SSAT1, SSAT2, SSATX, Ste27, Ta0374, VCA0947
ECTree
Source Tissue
Source Tissue on EC 2.3.1.57 - diamine N-acetyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
high ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
cDNA clone of human SSAT
brenda
-
-
brenda
-
brenda
-
primary fetal fibroblasts
brenda
-
brenda
-
brenda
-
-
brenda
-
brenda
-
brenda
-
-
brenda
-
colon cancer cells Caco-2 and HTC-116
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
high ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
-
-
brenda
-
high ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
-
-
brenda
-
-
brenda
-
melanoma-derived cells C8146C
brenda
-
brenda
-
TNFalpha can lead to the induction of NFkappaB signaling with a concomitant increase in spermidine/spermine N1-acetyltransferase expression
brenda
-
A549 and H157. TNFalpha can lead to the induction of NFkappaB signaling with a concomitant increase in spermidine/spermine N1-acetyltransferase expression
brenda
-
-
brenda
-
epithelial
brenda
-
C13
brenda
-
-
brenda
-
-
brenda
isozyme SSAT-2
brenda
-
-
brenda
-
-
brenda
-
human breast carcinoma cell line
brenda
-
-
brenda
-
-
brenda
-
lung-cancer derived cells
brenda
-
TNFalpha can lead to the induction of NFkappaB signaling with a concomitant increase in spermidine/spermine N1-acetyltransferase expression
brenda
-
brenda
-
brenda
-
enzyme expression in reduced in brain Brodmann areas,i.e. in BA4, BA8/9, and BA11, of suicide completers
brenda
-
highest activity
brenda
-
-
brenda
-
in breast tumors, SSAT is increased contributing to an increase in acetylated polyamines
brenda
-
colon cancer cells Caco-2 and HTC-116
brenda
-
induction by aspirin and different non-steroidal anti-inflammatory drugs
brenda
synovial fibroblasts from patients with rheumatoid arthritis or osteoarthritis
brenda
-
fetal
brenda
-
primary fetal fibroblasts
brenda
-
brenda
-
-
brenda
-
-
brenda
-
the enzyme is inducible in response to 5-fluorouracil or oxaliplatin in parental and drugresistant HCT116 cell lines
brenda
-
brenda
-
activity of SSAT is increased 28fold in tetracycline-induced cells. Increase in SSAT levels in HEK-293 cells leads to depletion of polyamines and elevation in the enzymatic activities of ornithine decarboxylase and S-adenosylmethionine decarboxylase, suggestive of a compensatory reaction to increased polyamine catabolism. Increased expression of SSAT also leads to DNA damage and G2 arrest
brenda
-
-
brenda
-
transient expression in
brenda
-
-
brenda
-
brenda
primary
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
high ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
-
-
brenda
-
brenda
-
-
brenda
-
low ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
-
-
brenda
-
carbon tetrachloride induced liver
brenda
-
brenda
-
-
-
brenda
-
brenda
-
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
overexpressed in transgenic mice
brenda
-
brenda
-
low ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
-
brenda
-
low ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
-
expression status of spermidine/spermine N1-acetyltransferase alters body fat accumulation by metabolically modulating tissue acetyl- and malonyl-CoA levels, thereby influencing fatty acid biosynthesis and oxidation
brenda
-
low ratio of splice variant SSATX to SSAT mRNA in syngenic rats
brenda
additional information
genes ssat1a, ssat1b, and ssat1c ares ubiquitously expressed in fish tissues st different levels, expression patterns, overview
brenda
additional information
-
genes ssat1a, ssat1b, and ssat1c ares ubiquitously expressed in fish tissues st different levels, expression patterns, overview
brenda
additional information
-
the enzyme is not detected in noncancerous human cells
brenda