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2.3.1.56: aromatic-hydroxylamine O-acetyltransferase

This is an abbreviated version!
For detailed information about aromatic-hydroxylamine O-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.56

Reaction

N-Hydroxy-4-acetylaminobiphenyl
+
N-Hydroxy-4-aminobiphenyl
=
N-Hydroxy-4-aminobiphenyl
+
N-acetoxy-4-aminobiphenyl

Synonyms

acetyltransferase, aromatic hydroxylamine, aromatic hydroxylamine acetyltransferase, arylhydroxamate acyltransferase, arylhydroxamate N,O-acetyltransferase, arylhydroxamic acid acyltransferase, arylhydroxamic acid N,O-acetyltransferase, arylhydroxamic acyltransferase, More, N,O-acetyltransferase, N-hydroxy-2-acetylaminofluorene N-O acyltransferase, NAT

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.56 aromatic-hydroxylamine O-acetyltransferase

Reference

Reference on EC 2.3.1.56 - aromatic-hydroxylamine O-acetyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hein, D.; Doll, M.; Rustan, T.; Ferguson, R.
Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions
Cancer Res.
55
3531-3536
1995
Homo sapiens
Manually annotated by BRENDA team
Sinclair, J.; Delgoda, R.; Noble, M.; Jarmin, S.; Goh, N.; Sim, E.
Purification, characterization and crystallization of an N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium
Protein Expr. Purif.
12
371-380
1998
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Hein, D.W.
Acetylator genotype and arylamine-induced carcinogenesis
Biochim. Biophys. Acta
948
37-66
1988
Oryctolagus cuniculus, Mesocricetus auratus, no activity in Cavia porcellus, no activity in Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Bartsch, H.; Dworkin, C.; Miller, E.C.; Miller, J.A.
Formation of electrophilic N-acetoxyarylamines in cytosols from rat mammary gland and other tissues by transacetylation from the carcinogen N-hydroxy-4-acetylaminobiphenyl
Biochim. Biophys. Acta
304
42-55
1973
Rattus norvegicus
Manually annotated by BRENDA team
Banks, R.B.; Hanna, P.E.
Arylhydroxamic acid N,O-acyltransferase. Apparent suicide inactivation by carcinogenic N-arylhydroxamic acids
Biochem. Biophys. Res. Commun.
91
1423-1429
1979
Mesocricetus auratus, Rattus norvegicus
Manually annotated by BRENDA team
Allaben, W.T.; King, C.M.
The purification of rat liver arylhydroxamic acid N,O-acyltransferase
J. Biol. Chem.
259
12128-12134
1984
Rattus norvegicus, Rattus norvegicus Sprague-Dawley CD
Manually annotated by BRENDA team
Marhevka, V.C.; Ebner, N.A.; Sehon, R.D.; Hanna, P.E.
Mechanism-based inactivation of N-arylhydroxamic acid N,O-acyltransferase by 7-substituted-N-hydroxy-2-acetamidofluorenes
J. Med. Chem.
28
18-24
1985
Mesocricetus auratus
Manually annotated by BRENDA team
Elfarra, A.A.; Yeh, H.M.; Hanna, P.E.
Synthesis and evaluation of N-(phenylalkyl)acetohydroxamic acids as potential substrates for N-arylhydroxamic acid N,O-acyltransferase
J. Med. Chem.
25
1189-1192
1982
Mesocricetus auratus, Rattus norvegicus
Manually annotated by BRENDA team
King, C.M.
Mechanism of reaction, tissue distribution, and inhibition of arylhydroxamic acid acyltransferase
Cancer Res.
34
1503-1515
1974
Rattus norvegicus
Manually annotated by BRENDA team
Land, S.J.; King, C.M.
Characterization of rat hepatic acetyltransferase
Environ. Health Perspect.
102
91-93
1994
Rattus norvegicus
-
Manually annotated by BRENDA team
Hanna, P.E.
N-acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation
Adv. Pharmacol.
27
401-430
1994
Homo sapiens, Mesocricetus auratus, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus
Manually annotated by BRENDA team
Arlt, V.M.; Glatt, H.; Muckel, E.; Pabel, U.; Sorg, B.L.; Schmeiser, H.H.; Phillips, D.H.
Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase
Carcinogenesis
23
1937-1945
2002
Homo sapiens
Manually annotated by BRENDA team
Jones, R.F.; Land, S.J.; King, C.M.
Recombinant rat and hamster N-acetyltransferases-1 and -2: relative rates of N-acetylation of arylamines and N,O-acyl transfer with arylhydroxamic acids
Carcinogenesis
17
1729-1733
1996
Mesocricetus auratus (P50292), Mesocricetus auratus (P50293), Rattus norvegicus (P50297), Rattus norvegicus (P50298)
Manually annotated by BRENDA team
Sone, T.; Zukowski, K.; Land, S.J.; Kin, C.M.; Martin, B.M.; Pohl, L.R.; Wang, C.Y.
Characteristics of a purified dog hepatic microsomal N,O-acyltransferase
Carcinogenesis
15
595-599
1994
Canis lupus familiaris, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Boteju, L.W.; Hanna, P.E.
Bioactivation of N-hydroxy-2-acetylaminofluorenes by N,O-acyltransferase: substituent effects on covalent binding to DNA
Carcinogenesis
14
1651-1657
1993
Homo sapiens
Manually annotated by BRENDA team