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2.3.1.56: aromatic-hydroxylamine O-acetyltransferase

This is an abbreviated version!
For detailed information about aromatic-hydroxylamine O-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.56

Reaction

N-Hydroxy-4-acetylaminobiphenyl
+
N-Hydroxy-4-aminobiphenyl
=
N-Hydroxy-4-aminobiphenyl
+
N-acetoxy-4-aminobiphenyl

Synonyms

acetyltransferase, aromatic hydroxylamine, aromatic hydroxylamine acetyltransferase, arylhydroxamate acyltransferase, arylhydroxamate N,O-acetyltransferase, arylhydroxamic acid acyltransferase, arylhydroxamic acid N,O-acetyltransferase, arylhydroxamic acyltransferase, More, N,O-acetyltransferase, N-hydroxy-2-acetylaminofluorene N-O acyltransferase, NAT

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.56 aromatic-hydroxylamine O-acetyltransferase

Engineering

Engineering on EC 2.3.1.56 - aromatic-hydroxylamine O-acetyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
G286E
-
small reduction in activity
I114T
-
strong reduction of the acetylation activity
K268R
-
slightly increased activity
R197Q
-
moderate reduction of acetylation activity
R64Q
-
moderate reduction of acetylation activity
additional information
-
nucleic acid substitutions C282T and C481T have no effect on activity