2.3.1.51: 1-acylglycerol-3-phosphate O-acyltransferase
This is an abbreviated version!
For detailed information about 1-acylglycerol-3-phosphate O-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.51
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2.3.1.51
-
adipose
-
triacylglycerols
-
triglyceride
-
lipodystrophy
-
phospholipid
-
acyl-coas
-
lipase
-
diacylglycerol
-
droplet
-
adipocytes
-
berardinelli-seip
-
lipolysis
-
glycerolipids
-
agpats
-
glycerophospholipids
-
chanarin-dorfman
-
hypertriglyceridemia
-
lysophospholipids
-
seipin
-
ichthyosis
-
perilipins
-
acanthosis
-
ichthyosiform
-
nigricans
-
erythroderma
-
identification-58
-
kennedy
-
acyl-acyl
-
endophilins
-
lipoatrophy
-
acyl-coa-dependent
-
medicine
- 2.3.1.51
- adipose
- triacylglycerols
- triglyceride
- lipodystrophy
- phospholipid
- acyl-coas
- lipase
- diacylglycerol
- droplet
- adipocytes
-
berardinelli-seip
-
lipolysis
- glycerolipids
- agpats
- glycerophospholipids
-
chanarin-dorfman
- hypertriglyceridemia
- lysophospholipids
-
seipin
- ichthyosis
-
perilipins
-
acanthosis
-
ichthyosiform
-
nigricans
- erythroderma
-
identification-58
-
kennedy
-
acyl-acyl
-
endophilins
-
lipoatrophy
-
acyl-coa-dependent
- medicine
Reaction
Synonyms
1-acyl-sn-glycero-3-phosphate acyltransferase, 1-acyl-sn-glycero-3-phosphate acyltransferase 1, 1-acyl-sn-glycero-3-phosphate acyltransferase 9, 1-acyl-sn-glycerol 3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate acyltransferas, 1-acyl-sn-glycerol-3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase, 1-acylglycero-3-phosphate acyltransferase, 1-acylglycerol 3-phosphate O-acyltransferase, 1-acylglycerol-3-phosphate acyltransferase, 1-acylglycerol-3-phosphate-O-acyltransferase, 1-acylglycerol-3-phosphate-O-acyltransferase 2, 1-acylglycerol-3-phosphate-O-acyltransferase isoform10/glycerol-3-phosphate acyltransferase isoform 3, 1-acylglycerol-3-phosphate-O-acyltransferase-1, 1-acylglycerolphosphate acyltransferase, 1-acylglycerophosphate acyltransferase, 1-Agpat2, ABHD5, acyl-CoA: sn-1-acyl-glycerol-3-phosphate acyltransferase, acyl-CoA:1-acylglycerol-sn-3-phosphate acyltransferase, acyl-CoA:lysophosphatidic acid acyltransferase, acyl-CoA:lysophospholipid acyltransferase, acyl-coenzyme A-dependent lysophosphatidic acid acyltransferase, acylglycerophosphate acyltransferase 4, acyltransferase, 1-acylglycerol phosphate, AGPAT, AGPAT/PlsC, AGPAT1, AGPAT10/GPAT3, AGPAT11, AGPAT2, AGPAT3, AGPAT4, AGPAT5, AGPAT6/GPAT4, AGPAT9, ALE1, At4g24160, AtLPAAt2, CGFI-58, cgi-58 protein, CGI-58/ABHD5, CHLREDRAFT_174358, coenzyme A-dependent lysophosphatidic acid, CrLPAAT1, CT775, CT_775, endoplasmic reticulum-located LPAT, ER-located LPAT, glycerol-3-phosphate acyltransferase-1, GPAT-1, ICT1 protein, LOA1, LPA acyltransferase, LPAAT, LPAAT-beta, LPAAT1, LPAAT2, LPAAT3, LPAAT4, LPAATbeta, LPAATdelta, LPAT, LPCAT1, LPCAT2, lysophosphatidic acid acyl transferase, lysophosphatidic acid acyltansferase, lysophosphatidic acid acyltransferase, lysophosphatidic acid acyltransferase 3, lysophosphatidic acid acyltransferase beta, lysophosphatidic acid ayltransferase, lysophosphatidic acid-acyltransferase, lysophosphatidic acid–specific acyltransferase, lysophosphatidyl acyltransferase, lysophosphatidyl acyltransferase 4, lysophosphatidylcholine acyltransferase 1, lysophospholipid acyltransferase, lysophospholipid:acyl-CoA acyltransferase, mAGPAT1, mAGPAT2, mAGPAT3, mAGPAT4, mAGPAT5, More, oleoyl-CoA lysophosphatidic acid acyltransferase, PCC8801_1274, plastidial LPAAT, plastidial lysophosphatidic acid acyltransferase, PlsC, PlsC4, PrLPAAT1, Scl1, ScLPAAT, SLC1, Slc1p, Slc4p, SlPlsC1, SMc00714 protein, SnGlycerol 3-P acyltransferase, TmPlsC, TM_1693, YPR139c
ECTree
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Reference on EC 2.3.1.51 - 1-acylglycerol-3-phosphate O-acyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hershenson, S.; Ernst-Fonberg, M.L.
Comparison of 1-acylglycerophosphate and glycerophosphate acyltransferases from Euglena microsomes
Int. J. Biochem.
16
219-223
1984
Euglena sp.
Bell, R.M.; Coleman, R.A.
Enzymes of triacylglycerol formation in mammals
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
16
87-111
1983
Rattus norvegicus
-
Frentzen, M.; Heinz, E.; McKeon, T.A.; Stumpf, P.K.
Specificities and selectivities of glycerol-3-phosphate acyltransferase and monoacylglycerol-3-phosphate acyltransferase from pea and spinach chloroplasts
Eur. J. Biochem.
129
629-636
1983
Pisum sativum, Spinacia oleracea
Frentzen, M.; Neuburger, M.; Joyard, J.; Douce, R.
Intraorganelle localization and substrate specificities of the mitochondrial acyl-CoA: sn-glycerol-3-phosphate O-acyltransferase and acyl-CoA: 1-acyl-sn-glycerol-3-phosphate O-acyltransferase from potato tubers and pea leaves
Eur. J. Biochem.
187
395-402
1990
Pisum sativum, Solanum tuberosum
Zaror-Behrens, G.; Kako, K.J.
Positional and fatty acid specificity of monoacyl- and diacylglycerol 3-phosphate formation by rabbit heart microsomes
Biochim. Biophys. Acta
441
1-13
1976
Oryctolagus cuniculus
Okuyama, H.; Wakil, S.J.
Positional specificities of acyl coenzyme A: glycerophosphate and acyl coenzyme A: monoacylglycerophosphate acyltransferases in Escherichia coli
J. Biol. Chem.
248
5197-5205
1973
Escherichia coli, Escherichia coli B / ATCC 11303
Okuyama, H.; Yamada, K.; Ikezawa, H.; Wakil, S.J.
Factors affecting the acyl selectivities of acyltransferases in Escherichia coli
J. Biol. Chem.
251
2487-2492
1976
Escherichia coli, Escherichia coli B / ATCC 11303
Yamada, K.; Okuyama, H.; Endo, Y.; Ikezawa, H.
Acyltransferase systems involved in phospholipid metabolism in Saccharomyces cerevisiae
Arch. Biochem. Biophys.
183
281-289
1977
Saccharomyces cerevisiae, Saccharomyces cerevisiae OC-2
Yamashita, S.; Hosaka, K.; Miki, Y.; Numa, S.
Glycerolipid acyltransferases from rat liver: 1-acylglycerophosphate acyltransferase, 1-acylglycerophosphorylcholine acyltransferase, and diacylglycerol acyltransferase
Methods Enzymol.
71
528-536
1981
Rattus norvegicus
Hill, E.E.; Lands, W.E.M.
Incorporation of long-chain and polyunsaturated acids into phosphatidate and phosphatidylcholine
Biochim. Biophys. Acta
152
645-648
1968
Rattus norvegicus
Yamashita, S.; Nakaya, N.; Miki, Y.; Numa, S.
Separation of 1-acylglycerolphosphate acyltransferase and 1-acylglycerolphosphorylcholine acyltransferase of rat liver microsomes
Proc. Natl. Acad. Sci. USA
72
600-603
1975
Rattus norvegicus
Miki, Y.; Hosaka, K.; Yamashita, S.; Handa, H.; Numa, S.
Acyl-acceptor specificities of 1-acylglycerolphosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase resolved from rat liver microsomes
Eur. J. Biochem.
81
433-441
1977
Rattus norvegicus
Rajasekharan, R.; Ray, T.K.; Cronan, J.E.
A direct nonchromatographic assay for 1-acyl-sn-glycerol-3-phosphate acyltransferase
Anal. Biochem.
173
376-382
1988
Escherichia coli
Kessels, J.M.M.; Ousen, H.; Van den Bosch, H.
Facilitated utilization of endogenously synthesized lysophosphatidic acid by 1-acylglycerophosphate acyltransferase from Escherichia coli
Biochim. Biophys. Acta
753
227-235
1983
Escherichia coli
Hares, W.; Frentzen, M.
Substrate specificities of the membrane-bound and partially purified microsomal acyl-CoA:1-acylglycerol-3-phosphate acyltransferase from etiolated shoots of Pisum sativum (L.)
Planta
185
124-131
1991
Pisum sativum
Hares, W.; Frentzen, M.
Properties of the microsomal acyl-CoA:sn-1-acyl-glycerol-3-phosphate acyltransferase from spinach (Spinacia oleracea L.) leaves
J. Plant Physiol.
131
49-59
1987
Spinacia oleracea
-
Waku, K.; Hayakawa, F.; Nakazawa, Y.
Regulation of the fatty acid pattern of phospholipids in rabbit sarcoplasmic reticulum. Specificity of glycerophosphate, 1-acylglycerophosphate and 2-acylglycerophosphorylcholine acyltransferase systems
J. Biochem.
82
671-677
1977
Oryctolagus cuniculus, Rattus norvegicus
Mizuno, M.; Sugiura, Y.; Okuyama, H.
Properties of acyl-coenzyme A:1-acylglycerophosphate acyltransferase and lipases in porcine erythrocyte membranes
J. Lipid Res.
25
843-850
1984
Homo sapiens, Sus scrofa
Marshall, M.O.; Knudsen, J.
The specificity of 1-acyl-sn-glycerol 3-phosphate acyltransferase in microsomal fractions from lactating cow mammary gland towards short, medium and long chain acyl-CoA esters
Biochim. Biophys. Acta
489
236-241
1977
Bos taurus
Inoue, M.; Murase, S.; Okuyama, H.
Acyl coenzyme A:phospholipid acyltransferases in porcine platelets discriminate between omega-3 and omega-6 unsaturated fatty acids
Arch. Biochem. Biophys.
231
29-37
1984
Rattus norvegicus, Sus scrofa
Davies, H.M.; Hawkins, D.J.; Nelsen, J.S.
Lysophosphatidic acid acyltransferase from immature coconut endosperm having medium chain length substrate specificity
Phytochemistry
39
989-996
1995
Cocos nucifera
-
Brown, A.P.; Brough, C.L.; Kroon, J.T.M.; Slabas, A.R.
Identification of a cDNA that encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase from Limnanthes douglasii
Plant Mol. Biol.
29
267-278
1995
Limnanthes douglasii (Q40119), Limnanthes douglasii (Q42870)
Swartley, J.S.; Balthazar, J.T.; Coleman, J.; Shafer, W.M.; Stephens, D.S.
Membrane glycerophospholipid biosynthesis in Neisseria meningitidis and Neisseria gonorrhoeae: identification, characterization, and mutagenesis of a lysophosphatidic acid acyltransferase
Mol. Microbiol.
18
401-412
1995
Neisseria gonorrhoeae (Q59601), Neisseria gonorrhoeae, Neisseria meningitidis (Q59618), Neisseria meningitidis
Knutzon, D.S.; Lardizabal, K.D.; Nelsen, J.S.; Bleibaum, J.L.; Davies, H.M.; Metz, J.G.
Cloning of a coconut endosperm cDNA encoding a 1-acyl-sn-glycerol-3-phosphate acyltransferase that accepts medium-chain-length substrates
Plant Physiol.
109
999-1006
1995
Cocos nucifera
Kume, K.; Shimizu, T.
cDNA cloning and expression of murine 1-acyl-sn-glycerol-3-phosphate acyltransferase
Biochem. Biophys. Res. Commun.
237
663-666
1997
Mus musculus
Weier, D.; Luhs, W.; Dettendorfer, J.; Frentzen, M.
sn-1-Acylglycerol-3-phosphate acyltransferase of Escherichia coli causes insertion of cis-11 eicosenoic acid into the sn-2 position of transgenic rapeseed oil
Mol. Breed.
4
39-46
1998
Brassica napus, Escherichia coli
Aguado, B.; Campbell, R.D.
Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex
J. Biol. Chem.
273
4096-4105
1998
Homo sapiens (Q99943), Homo sapiens
Morand, L.Z.; Patil, S.; Quasney, M.; German, J.B.
Alteration of the fatty acid substrate specificity of lysophosphatidate acyltransferase by site-directed mutagenesis
Biochem. Biophys. Res. Commun.
244
79-84
1998
Escherichia coli
Knutzon, D.S.; Hayes, T.R.; Wyrick, A.; Xiong, H.; Maelor Davies, H.; Voelker, T.A.
Lysophosphatidic acid acyltransferase from coconut endosperm mediates the insertion of laurate at the sn-2 position of triacylglycerols in lauric rapeseed oil and can increase total laurate levels
Plant Physiol.
120
739-746
1999
Cocos nucifera
Bourgis, F.; Kader, J.C.; Barret, P.; Renard, M.; Robinson, D.; Robinson, C.; Delseny, M.; Roscoe, T.J.
A plastidial lysophosphatidic acid acyltransferase from oilseed rape
Plant Physiol.
120
913-922
1999
Brassica napus
Wilmer, J.A.; Brown, A.P.; Forsyth, K.; Carnaby, S.; Barsby, T.; Slabas, A.R.
Limnanthes douglasii erucic acid-specific lysophospatidic acid acyltransferase activity in oilseed rape: an analysis of biochemical effects
Biochem. Soc. Trans.
28
964-966
2000
Limnanthes douglasii
Maisonneuve, S.; Bessoule, J.J.; Lessire, R.; Delseny, M.; Roscoe, T.J.
Mutagenesis of a plastidial lysophosphatidic acid acyltransferase
Biochem. Soc. Trans.
28
961-964
2000
Brassica napus (Q9XFW4)
Yamashita, A.; Kawagishi, N.; Miyashita, T.; Nagatsuka, T.; Sugiura, T.; Kume, K.; Shimizu, T.; Waku, K.
ATP-independent fatty acyl-coenzyme A synthesis from phospholipid: coenzyme A-dependent transacylation activity toward lysophosphatidic acid catalyzed by acyl-coenzyme A:lysophosphatidic acid acyltransferase
J. Biol. Chem.
276
26745-26752
2001
Mus musculus
Jolly, C.A.; Kannan, L.
Albumin stimulates lysophosphatidic acid acyltransferase activity in T-lymphocyte membranes
Lipids
37
475-480
2002
Rattus norvegicus
Haque, W.; Garg, A.; Agarwal, A.K.
Enzymatic activity of naturally occurring 1-acylglycerol-3-phosphate-O-acyltransferase 2 mutants associated with congenital generalized lipodystrophy
Biochem. Biophys. Res. Commun.
327
446-453
2005
Homo sapiens
Lu, B.; Jiang, Y.J.; Zhou, Y.; Xu, F.Y.; Hatch, G.M.; Choy, P.C.
Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart
Biochem. J.
385
469-477
2005
Mus musculus
Kim, H.U.; Huang, A.H.C.
Plastid lysophosphatidyl acyltransferase is essential for embryo development in Arabidopsis
Plant Physiol.
134
1206-1216
2004
Arabidopsis thaliana
Agarwal, A.K.; Barnes, R.I.; Garg, A.
Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity
Arch. Biochem. Biophys.
449
64-76
2006
Homo sapiens, Mus musculus
Ye, G.M.; Chen, C.; Huang, S.; Han, D.D.; Guo, J.H.; Wan, B.; Yu, L.
Cloning and characterization a novel human 1-acyl-sn-glycerol-3-phosphate acyltransferase gene AGPAT7
DNA Seq.
16
386-390
2005
Homo sapiens (Q643R3), Homo sapiens
Gale, S.E.; Frolov, A.; Han, X.; Bickel, P.E.; Cao, L.; Bowcock, A.; Schaffer, J.E.; Ory, D.S.
A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation
J. Biol. Chem.
281
11082-11089
2006
Homo sapiens (O15120)
Lu, B.; Jiang, Y.J.; Man, M.Q.; Brown, B.; Elias, P.M.; Feingold, K.R.
Expression and regulation of 1-acyl-sn-glycerol- 3-phosphate acyltransferases in the epidermis
J. Lipid Res.
46
2448-2457
2005
Mus musculus
Soerensen, B.M.; Furukawa-Stoffer, T.L.; Marshall, K.S.; Page, E.K.; Mir, Z.; Forster, R.J.; Weselake, R.J.
Storage lipid accumulation and acyltransferase action in developing flaxseed
Lipids
40
1043-1049
2005
Linum usitatissimum
Kim, H.U.; Li, Y.; Huang, A.H.
Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis
Plant Cell
17
1073-1089
2005
Arabidopsis thaliana (Q8GXU8), Arabidopsis thaliana (Q8L4Y2), Arabidopsis thaliana (Q8LG50), Arabidopsis thaliana (Q9LHN4), Arabidopsis thaliana (Q9SYC8), Arabidopsis thaliana
Yamashita, A.; Nakanishi, H.; Suzuki, H.; Kamata, R.; Tanaka, K.; Waku, K.; Sugiura, T.
Topology of acyltransferase motifs and substrate specificity and accessibility in 1-acyl-sn-glycero-3-phosphate acyltransferase 1
Biochim. Biophys. Acta
1771
1202-1215
2007
Homo sapiens (Q99943), Homo sapiens
Benghezal, M.; Roubaty, C.; Veepuri, V.; Knudsen, J.; Conzelmann, A.
SLC1 and SLC4 encode partially redundant acyl-coenzyme A 1-acylglycerol-3-phosphate O-acyltransferases of budding yeast
J. Biol. Chem.
282
30845-30855
2007
Saccharomyces cerevisiae (P33333), Saccharomyces cerevisiae (Q08548), Saccharomyces cerevisiae
Ghosh, A.K.; Ramakrishnan, G.; Chandramohan, C.; Rajasekharan, R.
CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid
J. Biol. Chem.
283
24525-24533
2008
Homo sapiens
Ghosh, A.K.; Ramakrishnan, G.; Rajasekharan, R.
YLR099C (ICT1) encodes a soluble Acyl-CoA-dependent lysophosphatidic acid acyltransferase responsible for enhanced phospholipid synthesis on organic solvent stress in Saccharomyces cerevisiae
J. Biol. Chem.
283
9768-9775
2008
Saccharomyces cerevisiae
Agarwal, A.K.; Sukumaran, S.; Bartz, R.; Barnes, R.I.; Garg, A.
Functional characterization of human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 9: cloning, tissue distribution, gene structure, and enzymatic activity
J. Endocrinol.
193
445-457
2007
Homo sapiens (Q8NF37), Homo sapiens
Schmidt, J.A.; Brown, W.J.
Lysophosphatidic acid acyltransferase 3 regulates Golgi complex structure and function
J. Cell Biol.
186
211-218
2009
Homo sapiens
Basconcillo, L.; Zaheer, R.; Finan, T.; McCarry, B.
A shotgun lipidomics study of a putative lysophosphatidic acid acyl transferase (PlsC) in Sinorhizobium meliloti
J. Chromatogr. B
877
2873-2882
2009
Sinorhizobium meliloti
Yuki, K.; Shindou, H.; Hishikawa, D.; Shimizu, T.
Characterization of mouse lysophosphatidic acid acyltransferase 3: an enzyme with dual functions in the testis
J. Lipid Res.
50
860-869
2009
Mus musculus (C4B4E7), Mus musculus, Mus musculus C57/BL6J (C4B4E7)
Montero-Moran, G.; Caviglia, J.M.; McMahon, D.; Rothenberg, A.; Subramanian, V.; Xu, Z.; Lara-Gonzalez, S.; Storch, J.; Carman, G.M.; Brasaemle, D.L.
CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase
J. Lipid Res.
51
709-719
2009
Homo sapiens, Mus musculus, Mus musculus (Q9DBL9)
Sukumaran, S.; Barnes, R.I.; Garg, A.; Agarwal, A.K.
Functional characterization of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 10/glycerol-3-phosphate acyltransferase isoform 3
J. Mol. Endocrinol.
42
469-478
2009
Homo sapiens
Ghosh, A.K.; Chauhan, N.; Rajakumari, S.; Daum, G.; Rajasekharan, R.
At4g24160, a soluble acyl-coenzyme A-dependent lysophosphatidic acid acyltransferase
Plant Physiol.
151
869-881
2009
Arabidopsis thaliana (O22975)
Maisonneuve, S.; Bessoule, J.J.; Lessire, R.; Delseny, M.; Roscoe, T.J.
Expression of Brassica napus microsomal Lysophosphatidic Acid Acyltransferase isozymes enhances seed oil content in Arabidopsis thaliana
Plant Physiol.
152
670-684
2009
Brassica napus (Q9XFW4), Brassica napus
Subauste, A.R.; Elliott, B.; Das, A.K.; Burant, C.F.
A role for 1-acylglycerol-3-phosphate-O-acyltransferase-1 in myoblast differentiation
Differentiation
80
140-146
2010
Mus musculus (O35083)
Koeberle, A.; Shindou, H.; Harayama, T.; Shimizu, T.
Role of lysophosphatidic acid acyltransferase 3 for the supply of highly polyunsaturated fatty acids in TM4 Sertoli cells
FASEB J.
24
4929-4938
2010
Mus musculus (C4B4E7), Mus musculus
Koeberle, A.; Shindou, H.; Harayama, T.; Yuki, K.; Shimizu, T.
Polyunsaturated fatty acids are incorporated into maturating male mouse germ cells by lysophosphatidic acid acyltransferase 3
FASEB J.
26
169-180
2012
Mus musculus (C4B4E7), Mus musculus
Pagac, M.; de la Mora, H.V.; Duperrex, C.; Roubaty, C.; Vionnet, C.; Conzelmann, A.
Topology of 1-acyl-sn-glycerol-3-phosphate acyltransferases SLC1 and ALE1 and related membrane-bound O-acyltransferases (MBOATs) of Saccharomyces cerevisiae
J. Biol. Chem.
286
36438-36447
2011
Saccharomyces cerevisiae (P33333), Saccharomyces cerevisiae (Q08548), Saccharomyces cerevisiae
Agarwal, A.K.; Sukumaran, S.; Cortes, V.A.; Tunison, K.; Mizrachi, D.; Sankella, S.; Gerard, R.D.; Horton, J.D.; Garg, A.
Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice
J. Biol. Chem.
286
37676-37691
2011
Homo sapiens (O15120), Homo sapiens (Q99943), Homo sapiens
Agarwal, A.K.; Garg, A.
Enzymatic activity of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 11: upregulated in breast and cervical cancers
J. Lipid Res.
51
2143-2152
2010
Homo sapiens (Q7L5N7), Homo sapiens
Prasad, S.S.; Garg, A.; Agarwal, A.K.
Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria
J. Lipid Res.
52
451-462
2011
Homo sapiens (Q9NRZ7), Homo sapiens (Q9NUQ2), Homo sapiens
Ayciriex, S.; Le Guedard, M.; Camougrand, N.; Velours, G.; Schoene, M.; Leone, S.; Wattelet-Boyer, V.; Dupuy, J.W.; Shevchenko, A.; Schmitter, J.M.; Lessire, R.; Bessoule, J.J.; Testet, E.
YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis
Mol. Biol. Cell
23
233-246
2012
Saccharomyces cerevisiae (Q06508), Saccharomyces cerevisiae
Rastegar, F.; Gao, J.L.; Shenaq, D.; Luo, Q.; Shi, Q.; Kim, S.H.; Jiang, W.; Wagner, E.R.; Huang, E.; Gao, Y.; Shen, J.; Yang, K.; He, B.C.; Chen, L.; Zuo, G.W.; Luo, J.; Luo, X.; Bi, Y.; Liu, X.; Li, M.; Hu, N.; Wang, L.; Luther, G.; Luu, H.H.; Haydon, R.C.; He, T.C.
Lysophosphatidic acid acyltransferase beta (LPAATbeta) promotes the tumor growth of human osteosarcoma
PLoS ONE
5
e14182
2010
Homo sapiens (O15120), Homo sapiens
Yu, X.H.; Prakash, R.R.; Sweet, M.; Shanklin, J.
Coexpressing Escherichia coli cyclopropane synthase with Sterculia foetida lysophosphatidic acid acyltransferase enhances cyclopropane fatty acid accumulation
Plant Physiol.
164
455-465
2014
Sterculia foetida (V9TK35), Sterculia foetida
Eto, M.; Shindou, H.; Shimizu, T.
A novel lysophosphatidic acid acyltransferase enzyme (LPAAT4) with a possible role for incorporating docosahexaenoic acid into brain glycerophospholipids
Biochem. Biophys. Res. Commun.
443
718-724
2014
Mus musculus (Q8K4X7), Mus musculus
Faris, R.; Fan, Y.; De Angulo, A.; Chapkin, R.; Degraffenried, L.; Jolly, C.
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential for murine CD4+ T cell metabolic activation
Biochim. Biophys. Acta
1841
1475-1482
2014
Mus musculus
-
Bradley, R.M.; Marvyn, P.M.; Aristizabal Henao, J.J.; Mardian, E.B.; George, S.; Aucoin, M.G.; Stark, K.D.; Duncan, R.E.
Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels
Biochim. Biophys. Acta
1851
1566-1576
2015
Mus musculus (Q8K4X7), Mus musculus
Lin, S.; Ikegami, M.; Moon, C.; Naren, A.P.; Shannon, J.M.
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) specifically interacts with phospholipid transfer protein starD10 to facilitate surfactant phospholipid trafficking in alveolar type II cells
J. Biol. Chem.
290
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Lysophosphatidic acid acyltransferase beta regulates mTOR signaling
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Homo sapiens
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Cocos nucifera (Q42670)
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Limnanthes douglasii (Q42870)
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Chlamydomonas reinhardtii (A8J0J0)
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High myristic acid content in the cyanobacterium Cyanothece sp. PCC 8801 results from substrate specificity of lysophosphatidic acid acyltransferase
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Rippkaea orientalis (B7K3J7), Rippkaea orientalis
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Increased DHA production in seed oil using a selective lysophosphatidic acid acyltransferase
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Possible role of different yeast and plant lysophospholipid acyl-CoA acyltransferases (LPLATs) in acyl remodelling of phospholipids
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Saccharomyces cerevisiae (P33333), Saccharomyces cerevisiae
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PrLPAAT4, a putative lysophosphatidic acid acyltransferase from Paeonia rockii, plays an important role in seed fatty acid biosynthesis
Molecules
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Paeonia rockii (KX256279), Paeonia rockii
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A two-helix motif positions the active site of lysophosphatidic acid acyltransferase for catalysis within the membrane bilayer
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Thermotoga maritima (Q9X219), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9X219), Thermotoga maritima ATCC 43589 (Q9X219), Thermotoga maritima JCM 10099 (Q9X219)
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