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2.3.1.50: serine C-palmitoyltransferase

This is an abbreviated version!
For detailed information about serine C-palmitoyltransferase, go to the full flat file.

Word Map on EC 2.3.1.50

Reaction

palmitoyl-CoA
+
L-serine
=
CoA
+
3-dehydro-D-sphinganine
+
CO2

Synonyms

3-oxosphinganine synthetase, acyl-CoA:serine C-2 acyltransferase decarboxylating, LCB1, LCB2, LCB2a, LCB2b, More, palmitoyltransferase, serine, serine palmitoyl transferase, serine palmitoyltransferase, serine palmitoyltransferase 1, serine palmitoyltransferase a, serine-palmitoyl transferase, serine-palmitoyltransferase, SPT, SPT1, SPT2, SPT3, SPTase, SPTLC1, SPTLC2, ssSPT, ssSPTa, Tsc3

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.50 serine C-palmitoyltransferase

KM Value

KM Value on EC 2.3.1.50 - serine C-palmitoyltransferase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.68 - 0.9
caproyl-CoA
9.6
L-alanine
-
C133W mutant protein, pH not specified in the publication, temperature not specified in the publication
0.1 - 10.6
L-serine
0.25 - 0.56
lauroyl-CoA
0.03 - 0.097
myristoyl-CoA
0.019 - 1.2
palmitoyl-CoA
0.0129
stearoyl-CoA
Rhizorhabdus wittichii
-
pH not specified in the publication, temperature not specified in the publication
1.79
[1,2,3-13C,2-15N] L-serine
-
at pH 8.1 and 37°C
4.09
[2,3,3-D] L-serine
-
at pH 8.1 and 37°C
3.64
[2-13C] L-serine
-
at pH 8.1 and 37°C
2.72
[3,3-D] L-serine
-
at pH 8.1 and 37°C
additional information
L-alanine