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of embryos
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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HAM1 or the HAM2 genes display an overlapping expression pattern, mainly in growing organs such as shoots and flower buds
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Qkf/Morf
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Artemia nauplii
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dormant
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in the embryonic cortex, nestin-positive precursors and betaII-tubulin positive neurons from E12-E13 primary cortical precursor cell culture
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from brain tumor
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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high expression öevel of CBP/p300 in hepatocarcinoma tissue
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P300/CBP-associated factor expression level analysis
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primary
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colon tumor cell line
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Betapolyomavirus macacae
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human embryonic kidney A293 cells
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expressed in embryonic lens. The lens-specific chromatin domain contains both promoter localized CBP on the background of locus spread-presence of CBP and p300
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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leukemic
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e.g. GFAP-positive astrocyytes and A2B5-positive oligodendrocyte precursors
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from neuronal tissue
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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DU145
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neuroblastoma
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HAM1 or the HAM2 genes display an overlapping expression pattern, mainly in growing organs such as shoots and flower buds
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in immune-related disease, HBO1 is upregulated in synovial fibroblasts, which are the key pathogenic factors contributing to the development and progression of rheumatoid arthritis
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decreased GCN5 in osteoporotic bone marrow
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decreased GCN5 in osteoporotic bone marrow
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mushroom bodies, expression of Enok
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HBO1
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the Qkf gene, in addition to being strongly expressed in the developing cerebral cortex and in adult neural stem cells, is also expressed in post-mitotic cells such as neurons
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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Betapolyomavirus macacae
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african green monkey kidney cell line CV-1 infected with SV40
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H4 acetylation at origins by HBO1 is cell-cycle regulated, with maximal activity at the G1/S transition
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cortex, CBP is expressed throughout embryogenesis, enzyme levels are decreasing postnatally
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E14.1, 129/Ola cells
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primary dermal
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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colon tumor cell line
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zMoz expression is restricted to the zebrafish head
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zMoz expression is restricted to the zebrafish head
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p53 modulation assay
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liver cancer cell line, histones are hyperacetylated in hepatocarcinomas
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tissue culture cell, HTC cells
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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meristem and stamen
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Tip60 co-localizes with the UHRF1/DNMT1 complex
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fetal
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fetal, expression of Moz
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fetal
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invariant natural killer T (iNKT) cells. Enzyme GCN5 promotes iNKT development during the maturation stage. iNKT cells undergo several well-defined developmental stages in the thymus. Dramatic accumulation of iNKT cells at the stage 0 in thymus of Gcn5 knockout mice
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invariant natural killer T (iNKT) cells. Enzyme GCN5 promotes iNKT development during the maturation stage. iNKT cells undergo several well-defined developmental stages in the thymus. Dramatic accumulation of iNKT cells at the stage 0 in thymus of Gcn5 knockout mice
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the embryonic cortex, nestin-positive precursors and betaII-tubulin positive neurons from E12-E13 primary cortical precursor cell culture
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the Qkf gene, in addition to being strongly expressed in the developing cerebral cortex and in adult neural stem cells, is also expressed in post-mitotic cells such as neurons
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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high GCN5 expression level which correlates with tumor size
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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meristematic part of root of embryos
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axe
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i.e. embryo
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i.e. embryo
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i.e. embryo
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i.e. embryo
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HBO1
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O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9 -
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leukemia cell line
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additional information
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ubiquitous expression of MORF protein in human tissue
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additional information
ubiquitous expression of MORF protein in human tissue
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additional information
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semiquantitative determination of enzyme in primary cancers of different tissues, overview. Hbo1 is approximately equimolar with the number of active replication origins in normal human fibroblasts but is an order of magnitude more abundant in both MCF7 and Saos-2 established cancer cell lines. Strong Hbo1 protein expression in carcinomas of the testis, ovary, breast, stomach/esophagus, and bladder
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additional information
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Tip60 is part of the evolutionarily conserved NuA4 complex
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additional information
aurora kinase A colocalalizes with ARD1 during cell division and cell migration, aurora A colocalizes with ARD1 at centrosomes during cell division in prophase, metaphase, anaphase, and telophase
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
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enzyme MOF/MYST1 is downregulated in ovarian, medulloblastoma, breast, colorectal and gastric carcinomas. Upregulated in NSCLC and oral tongue squamous cell carcinoma where it is associated with tumor growth
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
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GCN5 is upregulated in non-small cell lung carcinoma cells, colon cancer, and glioma
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additional information
HBO1 is highly expressed in testis or ovary. Tissue-specific acetyltransferase activity of HBO1
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
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KAT2B is underexpressed in hepatocellular carcinoma, esophageal squamous cell carcinoma, and ovarian and gastric cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
MYST2/HBO1 is overexpressed in different types of cancer
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additional information
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MYST2/HBO1 is overexpressed in different types of cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
Tip60 is downregulated in breast cancer
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additional information
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Tip60 is downregulated in breast cancer
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additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. In liver, protein levels of CBP are significantly reduced to during interbout arousal (IA) as compared to values for animals that are euthermic in the cold room. In skeletal muscle, CBP protein levels are significantly reduced during late torpor (LT). Levels of CBP do not fluctuate significantly over the course of the torpor-arousal cycle
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. In liver, protein levels of CBP are significantly reduced to during interbout arousal (IA) as compared to values for animals that are euthermic in the cold room. In skeletal muscle, CBP protein levels are significantly reduced during late torpor (LT). Levels of CBP do not fluctuate significantly over the course of the torpor-arousal cycle
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. In liver, protein levels of CBP are significantly reduced to during interbout arousal (IA) as compared to values for animals that are euthermic in the cold room. In skeletal muscle, CBP protein levels are significantly reduced during late torpor (LT). Levels of CBP do not fluctuate significantly over the course of the torpor-arousal cycle
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. In liver, protein levels of CBP are significantly reduced to during interbout arousal (IA) as compared to values for animals that are euthermic in the cold room. In skeletal muscle, CBP protein levels are significantly reduced during late torpor (LT). Levels of CBP do not fluctuate significantly over the course of the torpor-arousal cycle
brenda
additional information
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tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. In liver, protein levels of CBP are significantly reduced to during interbout arousal (IA) as compared to values for animals that are euthermic in the cold room. In skeletal muscle, CBP protein levels are significantly reduced during late torpor (LT). Levels of CBP do not fluctuate significantly over the course of the torpor-arousal cycle
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Levels of PCAF are significantly elevated over controls during four stages: entrance into torpor (EN), early torpor (ET), late torpor (LT) and early arousal. Protein levels of PCAF do not change significantly over torpor-arousal. In brown adipose tissue, protein levels of PCAF are significantly elevated during EN by 1.9fold over cold room (EC)
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Levels of PCAF are significantly elevated over controls during four stages: entrance into torpor (EN), early torpor (ET), late torpor (LT) and early arousal. Protein levels of PCAF do not change significantly over torpor-arousal. In brown adipose tissue, protein levels of PCAF are significantly elevated during EN by 1.9fold over cold room (EC)
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Levels of PCAF are significantly elevated over controls during four stages: entrance into torpor (EN), early torpor (ET), late torpor (LT) and early arousal. Protein levels of PCAF do not change significantly over torpor-arousal. In brown adipose tissue, protein levels of PCAF are significantly elevated during EN by 1.9fold over cold room (EC)
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Levels of PCAF are significantly elevated over controls during four stages: entrance into torpor (EN), early torpor (ET), late torpor (LT) and early arousal. Protein levels of PCAF do not change significantly over torpor-arousal. In brown adipose tissue, protein levels of PCAF are significantly elevated during EN by 1.9fold over cold room (EC)
brenda
additional information
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tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle decreases CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Levels of PCAF are significantly elevated over controls during four stages: entrance into torpor (EN), early torpor (ET), late torpor (LT) and early arousal. Protein levels of PCAF do not change significantly over torpor-arousal. In brown adipose tissue, protein levels of PCAF are significantly elevated during EN by 1.9fold over cold room (EC)
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle s decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. No significant fluctuations are observed for protein levels of HAT1 in liver over the torpor-arousal cycle. Protein levels of HAT1 do not change significantly over torpor-arousal. Protein levels of HAT1 in brown adipose tissue are significantly reduced during early torpor (ET) and interbout arousal (IA) to 0.6 of cold room (EC) level
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle s decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. No significant fluctuations are observed for protein levels of HAT1 in liver over the torpor-arousal cycle. Protein levels of HAT1 do not change significantly over torpor-arousal. Protein levels of HAT1 in brown adipose tissue are significantly reduced during early torpor (ET) and interbout arousal (IA) to 0.6 of cold room (EC) level
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle s decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. No significant fluctuations are observed for protein levels of HAT1 in liver over the torpor-arousal cycle. Protein levels of HAT1 do not change significantly over torpor-arousal. Protein levels of HAT1 in brown adipose tissue are significantly reduced during early torpor (ET) and interbout arousal (IA) to 0.6 of cold room (EC) level
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle s decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. No significant fluctuations are observed for protein levels of HAT1 in liver over the torpor-arousal cycle. Protein levels of HAT1 do not change significantly over torpor-arousal. Protein levels of HAT1 in brown adipose tissue are significantly reduced during early torpor (ET) and interbout arousal (IA) to 0.6 of cold room (EC) level
brenda
additional information
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tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscle s decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. No significant fluctuations are observed for protein levels of HAT1 in liver over the torpor-arousal cycle. Protein levels of HAT1 do not change significantly over torpor-arousal. Protein levels of HAT1 in brown adipose tissue are significantly reduced during early torpor (ET) and interbout arousal (IA) to 0.6 of cold room (EC) level
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscles decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Protein levels of GCN5L2 are significantly decreased during late torpor (LT) when compared to early torpor (ET), and subsequently increased during early arousal (EA)by 1.4fold over controls. GCN5L2 are significantly lowered during topor (EN), LT, EA and IA, but not during ET. Levels of GCN5L2 are also elevated during LT by 1.4fold before significantly decreasing during interbout arousal (IA) to 0.7 of cold room (EC)
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscles decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Protein levels of GCN5L2 are significantly decreased during late torpor (LT) when compared to early torpor (ET), and subsequently increased during early arousal (EA)by 1.4fold over controls. GCN5L2 are significantly lowered during topor (EN), LT, EA and IA, but not during ET. Levels of GCN5L2 are also elevated during LT by 1.4fold before significantly decreasing during interbout arousal (IA) to 0.7 of cold room (EC)
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscles decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Protein levels of GCN5L2 are significantly decreased during late torpor (LT) when compared to early torpor (ET), and subsequently increased during early arousal (EA)by 1.4fold over controls. GCN5L2 are significantly lowered during topor (EN), LT, EA and IA, but not during ET. Levels of GCN5L2 are also elevated during LT by 1.4fold before significantly decreasing during interbout arousal (IA) to 0.7 of cold room (EC)
brenda
additional information
tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscles decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Protein levels of GCN5L2 are significantly decreased during late torpor (LT) when compared to early torpor (ET), and subsequently increased during early arousal (EA)by 1.4fold over controls. GCN5L2 are significantly lowered during topor (EN), LT, EA and IA, but not during ET. Levels of GCN5L2 are also elevated during LT by 1.4fold before significantly decreasing during interbout arousal (IA) to 0.7 of cold room (EC)
brenda
additional information
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tissue-specific response of KATs, particularly in the adipose tissues where specific KATs (PCAF and GCN5L2), HAT activity, and H3K9ac increase in the metabolically active brown adipose tissue while HAT1, HAT activity and H3K9ac decrease in white adipose tissue. Liver shows significant increases in the KAT PCAF whereas skeletal muscles decreased CBP and GCN5L2. Both liver and skeletal muscle show no change in HAT activity and H3K9me3 increases in muscle during torpor. Protein levels of GCN5L2 are significantly decreased during late torpor (LT) when compared to early torpor (ET), and subsequently increased during early arousal (EA)by 1.4fold over controls. GCN5L2 are significantly lowered during topor (EN), LT, EA and IA, but not during ET. Levels of GCN5L2 are also elevated during LT by 1.4fold before significantly decreasing during interbout arousal (IA) to 0.7 of cold room (EC)
brenda
additional information
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Moz gene is expressed throughout the developing embryo and in most adult organs
brenda
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expression of GCN5 is decreased significantly in the bone tissue sections of ovariectomized mice or aged mice
brenda
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colocalization of Foxp3 and PCAF in nuclei of T-regulatory cells (Tregs)
brenda
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colocalization of Foxp3 and PCAF in nuclei of T-regulatory cells (Tregs)
brenda
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enzyme GCN5 expression analysis in different tissues from fasted (4 h) and anesthetized mice, overview
brenda
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expression of GCN5 is decreased significantly in the bone tissue sections of ovariectomized mice or aged mice
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brenda
additional information
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fairly constant levels of Hat1 protein throughout the cell cycle, soluble histone H4 Hat1-dependently acetylated on Lys12 is present in cells arrested at all cell cycle stages, G1, S, G2/M and also G0
brenda
additional information
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organ-specific expression patterns of HAT genes, overview
brenda
additional information
preformed enzyme form B is stored during embryogenesis to be available at the very early germination peroid
brenda
additional information
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preformed enzyme form B is stored during embryogenesis to be available at the very early germination peroid
brenda