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2.3.1.43: phosphatidylcholine-sterol O-acyltransferase

This is an abbreviated version!
For detailed information about phosphatidylcholine-sterol O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.43

Reaction

phosphatidylcholine
+
a sterol
=
1-acylglycerophosphocholine
+
a sterol ester

Synonyms

acyltransferase, lecithin-cholesterol, cholesterol transacyltransferase, LAT, LCAT, lecithin cholesterol acyl transferase, lecithin cholesterol acyltransferase, lecithin-cholesterol acyl transferase, lecithin-cholesterol acyltransferase, lecithin/cholesterol acyltransferase, lecithin: cholesterol acyltransferase, lecithin:cholesterol acyl-transferase, lecithin:cholesterol acyltransferase, lysolecithin acyltransferase, phospholipid-cholesterol acyltransferase, plasma lecithin-cholesterol acyltransferase, TgLCAT, TGME49_272420

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.43 phosphatidylcholine-sterol O-acyltransferase

Application

Application on EC 2.3.1.43 - phosphatidylcholine-sterol O-acyltransferase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
drug development
medicine
synthesis
baculovirus-mediated expression of LCAT in mammalian cells as a high-mannose glycoform suitable for deglycosylation by Endo H and its purification to homogeneity and characterization. Treatment of the protein with Endo H results in a recombinant protein product that retains its native form and is suitable for structural determination by X-ray crystallography