2.3.1.42: glycerone-phosphate O-acyltransferase
This is an abbreviated version!
For detailed information about glycerone-phosphate O-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.42
-
2.3.1.42
-
peroxisomal
-
plasmalogens
-
zellweger
-
chondrodysplasia
-
rhizomelic
-
punctata
-
glycerolipids
-
phytanic
-
alkyl-dhap
-
hemochromatosis
-
adrenoleukodystrophy
-
stippling
-
cerebro-hepato-renal
-
lignoceric
-
refsum
-
medicine
-
analysis
- 2.3.1.42
- peroxisomal
- plasmalogens
- zellweger
-
chondrodysplasia
-
rhizomelic
- punctata
- glycerolipids
-
phytanic
- alkyl-dhap
- hemochromatosis
- adrenoleukodystrophy
-
stippling
-
cerebro-hepato-renal
-
lignoceric
- refsum
- medicine
- analysis
Reaction
Synonyms
acyltransferase, dihydroxyacetone phosphate, DAP-AT, DAT, DHAP acyltransferase, DHAP-AT, DHAPAT, dihydroxyacetone phosphate acyl-transferase, dihydroxyacetone phosphate acyltransferase, dihydroxyacetone-phosphate acyltransferase, dihydroxyacetonephosphate acyltransferase, glyceronephosphate O-acyltransferase, GNPAT, LmDAT, male sterility protein, TtFARAT
ECTree
2.3.1.42 glycerone-phosphate O-acyltransferaseAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 2.3.1.42 - glycerone-phosphate O-acyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
acyl-CoA + glycerone phosphate
CoA + 1-acylglycerone phosphate
-
-
-
?
acyl-CoA + glycerone phosphate
CoA + 1-acylglycerone phosphate
-
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
-
enzyme is essential for biosynthesis of plasmalogens and nonetherlipids, the peroxisomal isozymes does not contribute to nonetherlipid biosynthesis
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
-
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
-
enzyme is essential for biosynthesis of plasmalogens and nonetherlipids, the peroxisomal isozymes does not contribute to nonetherlipid biosynthesis
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
enzyme is involved in biosynthesis of plasmalogens, regulating enzyme
-
-
?
dihydroxyacetone phosphate + acyl-CoA
1-acyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + acyl-CoA
1-acyl-glycerone phosphate + CoA
-
the enzyme performs the initial and obligatory step in the biosynthesis of ether lipids in most organisms that synthesize alkylglycerolipids and is important for rapid growth and survival at high cell density and essential for virulence, overview, lack of DAT causes a major alteration in parasite division during the logarithmic phase of growth, an accelerated cell death during stationary phase, and loss of virulence in mice
-
-
?
dihydroxyacetone phosphate + acyl-CoA
1-acyl-glycerone phosphate + CoA
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
r
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
r
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
initiates glycerolipid, especially ether-linked glycerolipid, biosynthesis in higher eukaryotes
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
peroxisomal enzyme involved in ether lipid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
recombinant in Saccharomyces cerevisiae cells
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
recombinant in Saccharomyces cerevisiae cells
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
peroxisomal enzyme involved in ether lipid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
peroxisomal enzyme involved in ether lipid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
no precursor for glycerol ether lipids
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
initiates glycerolipid, especially ether-linked glycerolipid, biosynthesis in higher eukaryotes
-
-
?
additional information
?
-
-
enzyme activity is reduced with disorders: neonatal adrenoleukodystrophy, infantile Refsum disease, and hyperpipecolic acidemia
-
-
?
additional information
?
-
-
enzyme amount is reduced by 90% in Zellweger syndrome
-
-
?
additional information
?
-
-
enzyme amount is reduced by 90% in Zellweger syndrome
-
-
?
additional information
?
-
-
patients affected with rhizomelic chondrodysplasia punctata show reduced enzyme activity due to a defect in peroxisomal targeting
-
-
?
additional information
?
-
-
patients affected with rhizomelic chondrodysplasia punctata show reduced enzyme activity due to a defect in peroxisomal targeting
-
-
?
additional information
?
-
-
the enzyme is involved in the first step of plasmalogen biosynthesis, overview
-
-
?
