2.3.1.41: beta-ketoacyl-[acyl-carrier-protein] synthase I

This is an abbreviated version!
For detailed information about beta-ketoacyl-[acyl-carrier-protein] synthase I, go to the full flat file.

Word Map on EC 2.3.1.41

2.3.1.41

polyketide

cerulenin

malonyl-coa

thioesterase

elongase

enoyl

thiolactomycin

transacylase

mycolic

malonyl-acp

acyl-acps

very-long-chain

dehydrase

4'-phosphopantetheine

cuphea

vlcfas

cis-vaccenic

malonyl-coa:acp

actinorhodin

platensimycin

acetyl-acp

drug development

6-methylsalicylic

3-oxoacyl-acps

claisen

pharmacology

nutrition

medicine

Reaction

Synonyms

3-ketoacyl-ACP synthase, 3-ketoacyl-acyl carrier protein synthase, 3-ketoacyl-acyl-carrier protein synthase I, 3-oxoacyl synthase, 3-oxoacyl-[acyl-carrier-protein] synthase, acyl-malonyl(acyl-carrier-protein)-condensing enzyme, B-ketoacyl-ACP synthase I, beta-ketoacyl ACP synthase I, beta-ketoacyl acyl carrier protein synthase, beta-ketoacyl acyl carrier protein synthase I, beta-ketoacyl synthase, beta-ketoacyl synthetase, beta-ketoacyl [ACP] synthase, beta-ketoacyl-ACP synthase, beta-ketoacyl-ACP synthase I, beta-ketoacyl-ACP synthetase, beta-ketoacyl-ACP-synthase, beta-ketoacyl-ACP-synthase I, beta-ketoacyl-acyl carrier protein synthase I, beta-ketoacyl-acyl carrier protein synthetase, beta-ketoacyl-acyl-ACP synthase I, beta-ketoacyl-CoA synthase-I, beta-ketoacyl-[acyl carrier protein (ACP)] synthase III, beta-ketoacyl-[acyl carrier protein] synthase, beta-ketoacyl-[acyl carrier protein] synthase I, beta-ketoacyl-[acyl-carrier-protein] synthase I, beta-ketoacylsynthase, condensing enzyme, Cys-His-His-type beta-ketoacyl-acyl carrier protein synthase, DpsC, elongase, elongating beta-ketoacyl-acyl carrier protein synthase, FabB, FabBF, FabH, fatty acid condensing enzyme, KAS, Kas A, KAS I, KasA, KasI, KASI-1, KASI-2, KCSI, More, OsKASI, synthase, 3-oxoacyl-[acyl-carrier-protein]

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I

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Results	in table
15	Activating Compound
16618	AA Sequence
12	Application
1	CAS Registry Number
29	Cloned(Commentary)
14	Crystallization (Commentary)
36	Disease/ Diagnostics
11	General Information
11	General Stability
3	IC50 Value
96	Inhibitors
17	kcat/KM [mM/s]
3	Ki Value [mM]
65	KM Value [mM]
15	Localization
1	Metals/Ions
49	Molecular Weight [Da]
38	Natural Substrates/ Products (Substrates)
281	Organism
1	Oxidation Stability
26	Pathway
328	PDB ID
21	pH Optimum
9	pH Range
2	Posttranslational Modification
47	Protein Variants
42	Purification (Commentary)
23	Reaction
23	Reaction Type
80	Reference
56	Source Tissue
41	Specific Activity [micromol/min/mg]
9	Storage Stability
242	Substrates and Products (Substrate)
31	Subunits
93	Synonyms
1	Systematic Name
20	Temperature Optimum [°C]
2	Temperature Stability [°C]
36	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.1.41 - beta-ketoacyl-[acyl-carrier-protein] synthase I

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4-hexadecenoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein]

3-oxo-6-octadecenoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]

Coriandrum sativum

reaction is part of petroselinic acid biosynthesis, synthase IV

486948

acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein]

3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]

21 entries

an acyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein]

a 3-oxoacyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein]

8 entries

an acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein]

a 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]

Helianthus annuus

the endoplasmic reticulum enzyme is involved in synthesis of very long chain fatty acids

674095

cis-3-decenoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein]

3-oxo-cis-5-dodecenoyl-[acyl-carrier protein] + acyl-carrier protein

Escherichia coli

key step in the unsaturated fatty acid, UFA, synthesis pathway. FabB is negatively regulated by the FabR protein

704553

the product is not incorporated into the complex lipids of the bacterium

additional information

4 entries