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2.3.1.37: 5-aminolevulinate synthase

This is an abbreviated version!
For detailed information about 5-aminolevulinate synthase, go to the full flat file.

Word Map on EC 2.3.1.37

Reaction

succinyl-CoA
+
glycine
=
5-aminolevulinate
 +
CoA
 +
CO2

Synonyms

5-ALA synthase, 5-ALAS, 5-aminolevulinate synthase, 5-aminolevulinate synthetase, 5-aminolevulinic acid synthase, 5-aminolevulinic acid synthetase, ALA, ALA synthase, ALA synthetase, ALA-S, ALAS, ALAS2, alpha-aminolevulinic acid synthase, aminolevulinate synthase, aminolevulinate synthase 2, aminolevulinate synthetase, aminolevulinic acid synthase, aminolevulinic acid synthase 2, aminolevulinic acid synthetase, aminolevulinic synthetase, delta-ALAS, delta-aminolevulinate synthase, delta-aminolevulinate synthetase, delta-aminolevulinic acid synthase, delta-aminolevulinic acid synthase 2, delta-aminolevulinic acid synthetase, delta-aminolevulinic synthetase, erythroid 5-aminolevulinate synthase, erythroid-specific 5-aminolevulinate synthase, Hem1, hemA, HemT, mALAS-2, sigma-aminolevulinate synthase, synthase, aminolevulinate, synthetase, aminolevulinate

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.37 5-aminolevulinate synthase

Specific Activity

Specific Activity on EC 2.3.1.37 - 5-aminolevulinate synthase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0037
-
crude enzyme extract
0.0057
-
maximal enzyme activity after 3 weeks of storage of tubers at 0-15°C at 30 lux
0.018
-
purified enzyme
0.035
-
purified enzyme
0.091
-
purified enzyme
0.16
-
purified enzyme
0.167
-
isozyme II
0.35
-
purified enzyme
0.375
-
purified isozyme I
0.558
-
purified enzyme
0.58
-
purified enzyme
0.62
-
purified enzyme
0.65
-
purified enzyme
1.07
mutant C281P of isoform HemT, pH and temperature not specified in the publication
1.13
isoform HemA, pH and temperature not specified in the publication
1.22
-
purified enzyme
1.34
-
purified enzyme
1.87
-
purified erythroid-specific isoform
1.89
isoform HemA, pH and temperature not specified in the publication
2.17
-
purified enzyme
2.17 - 2.83
-
purified enzyme
2.22
-
purified enzyme
additional information