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2.3.1.37: 5-aminolevulinate synthase

This is an abbreviated version!
For detailed information about 5-aminolevulinate synthase, go to the full flat file.

Word Map on EC 2.3.1.37

Reaction

succinyl-CoA
+
glycine
=
5-aminolevulinate
+
CoA
+
CO2

Synonyms

5-ALA synthase, 5-ALAS, 5-aminolevulinate synthase, 5-aminolevulinate synthetase, 5-aminolevulinic acid synthase, 5-aminolevulinic acid synthetase, ALA, ALA synthase, ALA synthetase, ALA-S, ALAS, ALAS2, alpha-aminolevulinic acid synthase, aminolevulinate synthase, aminolevulinate synthase 2, aminolevulinate synthetase, aminolevulinic acid synthase, aminolevulinic acid synthase 2, aminolevulinic acid synthetase, aminolevulinic synthetase, delta-ALAS, delta-aminolevulinate synthase, delta-aminolevulinate synthetase, delta-aminolevulinic acid synthase, delta-aminolevulinic acid synthase 2, delta-aminolevulinic acid synthetase, delta-aminolevulinic synthetase, erythroid 5-aminolevulinate synthase, erythroid-specific 5-aminolevulinate synthase, Hem1, hemA, HemT, mALAS-2, sigma-aminolevulinate synthase, synthase, aminolevulinate, synthetase, aminolevulinate

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.37 5-aminolevulinate synthase

Molecular Weight

Molecular Weight on EC 2.3.1.37 - 5-aminolevulinate synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
105000
-
enzyme I, gel filtration
107000 - 110000
-
stripped form, sucrose density gradient centrifugation, gel filtration, disc gel electrophoresis
110000
112000
-
gel filtration
115000
-
gel filtration
118000
-
dimer, gel filtration
120000
-
gel filtration
158000
-
gel filtration
178000
-
cytosol, gel filtration
200000
-
gel filtration
218000
-
tetramer of enzyme and native activator protein, gel filtration
295000
-
gel filtration, presence of NaCl
49000
500000
-
gel filtration, absence of NaCl
51000
-
2 * 51000, cytosol, SDS-PAGE
52000
x * 54000, recombinant wild-type enzyme, SDS-PAGE, x * 52000, recombinant mutant F557X, SDS-PAGE
53000
-
2 * 53000, SDS-PAGE
54000
56000
57000
-
gel filtration
58000
61000
-
gel filtration
61000 - 64000
-
isoenzyme II, gel filtration
62000 - 68000
-
gel filtration
62200
-
2 * 62200, SDS-PAGE
63000
-
x * 63000, about, SDS-PAGE
64840
-
erythroid-specific isoform precursor, DNA-sequence determination
65000 - 70000
-
-
68000
70000
-
mitochondrial enzyme, cytosolic enzyme is a precursor of the mitochondrial enzyme
76000
-
precursor form, gel filtration
77000
-
mitochondria, gel filtration
80000
-
active form, gel filtration
81000
-
gel filtration
87000
93000
-
gel filtration
97000
-
gel filtration
additional information