2.3.1.36: D-amino-acid N-acetyltransferase

This is an abbreviated version!
For detailed information about D-amino-acid N-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyltransferase, D-amino acid, D-amino acid acetyltransferase, D-amino acid-alpha-N-acetyltransferase, DNT, Hpa3p

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.36 D-amino-acid N-acetyltransferase

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Results	in table
5	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
5	Inhibitors
8	KM Value [mM]
3	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
4	Organism
2	Pathway
3	pH Optimum
3	Purification (Commentary)
2	Reaction
1	Reaction Type
4	Reference
2	Specific Activity [micromol/min/mg]
1	Storage Stability
45	Substrates and Products (Substrate)
2	Subunits
6	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Substrates Products

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of the Enzyme Summary Page.

Substrates Products on EC 2.3.1.36 - D-amino-acid N-acetyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

acetyl-CoA + a D-amino acid

CoA + an N-acetyl-D-amino acid

3 entries

acetyl-CoA + D-alanine

CoA + N-acetyl-D-alanine

2 entries

acetyl-CoA + D-alpha-aminobutyrate

CoA + N-acetyl-D-alpha-aminobutyrate

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-arginine

CoA + N-acetyl-D-arginine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-asparaginate

CoA + N-acetyl-D-asparaginate

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-asparagine

CoA + N-acetyl-D-asparagine

2 entries

acetyl-CoA + D-cysteine

CoA + N-acetyl-D-cysteine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-cystine

CoA + N-acetyl-D-cystine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-glutamine

CoA + N-acetyl-D-glutamine

2 entries

acetyl-CoA + D-histidine

CoA + N-acetyl-D-histidine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-isoleucine

CoA + N-acetyl-D-isoleucine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-leucine

CoA + N-acetyl-D-leucine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-lysine

CoA + N-acetyl-D-lysine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-methionine

CoA + N-acetyl-D-methionine

2 entries

acetyl-CoA + D-norleucine

CoA + N-acetyl-D-norleucine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-norvaline

CoA + N-acetyl-D-norvaline

2 entries

acetyl-CoA + D-phenylalanine

CoA + N-acetyl-D-phenylalanine

2 entries

acetyl-CoA + D-proline

CoA + N-acetyl-D-proline

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-serine

CoA + N-acetyl-D-serine

2 entries

acetyl-CoA + D-threonine

CoA + N-acetyl-D-threonine

2 entries

acetyl-CoA + D-tryptophan

CoA + N-acetyl-D-tryptophan

2 entries

acetyl-CoA + D-tyrosine

CoA + N-acetyl-D-tyrosine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-valine

CoA + N-acetyl-D-valine

2 entries

acetyl-CoA + norleucine

CoA + N-acetyl-D-norleucine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

propionyl-CoA + D-alanine

CoA + N-propionyl-D-alanine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

propionyl-CoA + D-allo-isoleucine

CoA + N-propionyl-D-allo-isoleucine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

propionyl-CoA + D-glutamine

CoA + N-propionyl-D-glutamine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

propionyl-CoA + D-leucine

CoA + N-propionyl-D-leucine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

propionyl-CoA + D-serine

CoA + N-propionyl-D-serine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

propionyl-CoA + D-tryptophan

CoA + N2-propionyl-D-tryptophan

Saccharomyces cerevisiae

-

-

486807

-

486807

ir

additional information

?

-

2 entries

acetyl-CoA + a D-amino acid

CoA + an N-acetyl-D-amino acid

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + a D-amino acid

CoA + an N-acetyl-D-amino acid

Saccharomyces cerevisiae

-

substrate specificity, overview

657695

-

-

?

acetyl-CoA + a D-amino acid

CoA + an N-acetyl-D-amino acid

Saccharomyces cerevisiae

-

D-amino acids are toxic to Saccharomyces cerevisiae but are detoxified with D-amino acid-N-acetyltransferase by N-acetylation preceding removal from yeast cells

671643

-

-

?

acetyl-CoA + D-alanine

CoA + N-acetyl-D-alanine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-alanine

CoA + N-acetyl-D-alanine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-asparagine

CoA + N-acetyl-D-asparagine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-asparagine

CoA + N-acetyl-D-asparagine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-glutamine

CoA + N-acetyl-D-glutamine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-glutamine

CoA + N-acetyl-D-glutamine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-methionine

CoA + N-acetyl-D-methionine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-methionine

CoA + N-acetyl-D-methionine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-norvaline

CoA + N-acetyl-D-norvaline

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-norvaline

CoA + N-acetyl-D-norvaline

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-phenylalanine

CoA + N-acetyl-D-phenylalanine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-phenylalanine

CoA + N-acetyl-D-phenylalanine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-serine

CoA + N-acetyl-D-serine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-serine

CoA + N-acetyl-D-serine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-threonine

CoA + N-acetyl-D-threonine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-threonine

CoA + N-acetyl-D-threonine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

acetyl-CoA + D-tryptophan

CoA + N-acetyl-D-tryptophan

Saccharomyces cerevisiae

-

-

657695, 660039

-

-

?

acetyl-CoA + D-tryptophan

CoA + N-acetyl-D-tryptophan

Saccharomyces cerevisiae

-

-

486807

-

486807

ir

acetyl-CoA + D-valine

CoA + N-acetyl-D-valine

Saccharomyces cerevisiae

-

-

657695

-

-

?

acetyl-CoA + D-valine

CoA + N-acetyl-D-valine

Saccharomyces cerevisiae

-

-

486807

-

-

ir

additional information

?

-

Saccharomyces cerevisiae

-

L-isomers are not accepted, glycine and D-taurine are poor substrates, propionyl-CoA can replace acetyl-CoA

486807

-

-

?

additional information

?

-

Saccharomyces cerevisiae

-

no activity with L-lysine, D-proline, and D-aspartate, D-glutamate is a poor substrate

657695

-

-

?