2.3.1.32: lysine N-acetyltransferase
This is an abbreviated version!
For detailed information about lysine N-acetyltransferase, go to the full flat file.
Word Map on EC 2.3.1.32
-
2.3.1.32
-
coactivator
-
chromatin
-
transactivation
-
e1a
-
creb-binding
-
gnat
-
adenovirus
-
oncoproteins
-
deacetylases
-
hdacs
-
nucleosomal
-
creb
-
hypoxia-inducible
-
deacetylation
-
element-binding
-
bromodomains
-
p300-mediated
-
smads
-
hyperacetylation
-
acetylase
-
trichostatin
-
h3k27ac
-
corepressors
-
non-histone
-
p300-dependent
-
accoa
-
p53-dependent
-
myod
-
p53-mediated
-
tax
-
htlv-1
-
medicine
-
brd4
-
pharmacology
-
tata-binding
-
selangor
-
h3k4me1
- 2.3.1.32
-
coactivator
- chromatin
-
transactivation
- e1a
-
creb-binding
-
gnat
- adenovirus
- oncoproteins
- deacetylases
- hdacs
-
nucleosomal
- creb
-
hypoxia-inducible
-
deacetylation
-
element-binding
-
bromodomains
-
p300-mediated
- smads
-
hyperacetylation
-
acetylase
-
trichostatin
-
h3k27ac
-
corepressors
-
non-histone
-
p300-dependent
- accoa
-
p53-dependent
- myod
-
p53-mediated
- tax
- htlv-1
- medicine
- brd4
- pharmacology
-
tata-binding
-
selangor
-
h3k4me1
Reaction
Synonyms
acetyltransferase p300, acetyltransferase, lysine, ATase1, ATase2, Cbp, cyclic adenosine monophosphate response element-binding binding protein, Esa1, Gcn5, GCN5-A, GCN5-related N-acetyltransferase, GNAT, H4 lysine acetyltransferase, HAT, histone/protein lysine acetyltransferase, KAT, lysine acetyltransferase, NuA4, p/CAF, p300, p300 acetyltransferase, p300/CBP, PCAF, Rtt109 histone acetyltransferase, SePat
ECTree
Advanced search results
IC50 Value
IC50 Value on EC 2.3.1.32 - lysine N-acetyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
additional information
Homo sapiens
-
10, 25, 50 microM inhibit FLAG-tagged recombinant PCAF in vitro with an IC50 beyond 50 microM with purified human HeLa core histone as substrate
-
additional information
additional information
Homo sapiens
-
Hep-G2 hepatocarcinoma cells: with 5 microM plumbagin 50% reduction of histone H3 acetylation, with 25 microM 90% reduction, significant overall acetylation status of histones, prominent reduction in H3 and H4, immunofluorescence analysis (anti-acetylated histone H3 polyclonal antibodies) of HeLa cells (treated with deacetylase inhibitors to induce histone acetylation) confirm the inhibitory effect of plumbagin with 5 microM inhibitor, with 25 microM almost complete reduction in acetylation level
-
additional information
additional information
Mus musculus
-
significant decrease of histone acetylation in plumbagin treated mouse liver in vivo 6 h after intraperitoneal injection of 25 mg plumbagin/kg body mass
-