2.3.1.29: glycine C-acetyltransferase

This is an abbreviated version!
For detailed information about glycine C-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.29

2.3.1.29

l-threonine

pyridoxal

5'-phosphate

5-aminolevulinate

1.1.1.103

8-amino-7-oxononanoate

5'-phosphate-dependent

7-keto-8-aminopelargonic

biofs

synthesis

Reaction

Synonyms

2-amino-3-ketobutyrate CoA ligase, 2-amino-3-ketobutyrate coenzyme A ligase, 2-amino-3-ketobutyrate-CoA ligase, 2-amino-3-oxobutyrate CoA ligase, acetyltransferase, glycine, alpha-amino-beta-oxobutyrate CoA-ligase, aminoacetone synthase, aminoacetone synthetase, glycine acetyltransferase, KBL

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.29 glycine C-acetyltransferase

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Results	in table
5	Activating Compound
13831	AA Sequence
2	Application
1	CAS Registry Number
10	Cloned(Commentary)
12	Cofactor
1	Crystallization (Commentary)
1	General Information
5	General Stability
34	Inhibitors
2	Ki Value [mM]
10	KM Value [mM]
9	Localization
21	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
119	Organism
5	Pathway
28	PDB ID
6	pH Optimum
2	pH Range
1	pH Stability
2	Posttranslational Modification
7	Purification (Commentary)
5	Reaction
1	Reaction Type
19	Reference
9	Source Tissue
5	Specific Activity [micromol/min/mg]
41	Substrates and Products (Substrate)
10	Subunits
15	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 2.3.1.29 - glycine C-acetyltransferase

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acetyl-CoA + aminomalonate

CoA + CO2 + 2-amino-3-oxobutanoate

Bos taurus

486744

same product as in reaction with glycine, aminomalonate is decarboxylated to glycine by the enzyme, in the absence of acetyl-CoA: glycine is the product

486744

acetyl-CoA + glycine

CoA + 2-amino-3-oxobutanoate

34 entries

acetyl-CoA + glycine

CoA + L-2-amino-3-oxobutanoate

2 entries

acetyl-CoA + L-alanine

CoA + ?

Thermus thermophilus

685670

n-butyryl-CoA + glycine

CoA + 2-amino-3-oxohexanoate

Escherichia coli

reaction at 16% the rate of acetyl-CoA

486740

n-propionyl-CoA + glycine

CoA + 2-amino-3-oxopentanoate

Escherichia coli

reaction at 127% the rate of acetyl-CoA

486740

additional information

Escherichia coli

the enzyme catalyzes the exchange of pro-R hydrogen of glycine with protons in the medium

736143