2.3.1.251: lipid IVA palmitoyltransferase
This is an abbreviated version!
For detailed information about lipid IVA palmitoyltransferase, go to the full flat file.
Word Map on EC 2.3.1.251
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2.3.1.251
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palmitoylated
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lipopolysaccharide
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typhimurium
-
toll-like
-
palmitate
-
3-o-deacylase
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two-component
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tlr4-signaling
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phospholipids
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interior
-
ruler
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leaflet
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phopq
-
deacylase
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aeruginosa
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synthesis
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medicine
- 2.3.1.251
-
palmitoylated
- lipopolysaccharide
- typhimurium
-
toll-like
- palmitate
-
3-o-deacylase
-
two-component
-
tlr4-signaling
- phospholipids
-
interior
-
ruler
- leaflet
-
phopq
-
deacylase
- aeruginosa
- synthesis
- medicine
Reaction
Synonyms
crcA, lipid A palmitoyltransferase, PA1343, PagP
ECTree
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Substrates Products
Substrates Products on EC 2.3.1.251 - lipid IVA palmitoyltransferase
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REACTION DIAGRAM
1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + 3-O-deacyl lipid X
2-acyl-sn-glycero-3-phosphocholine + lipid X
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA
2-acyl-sn-glycero-3-phosphocholine + lipid IVB
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-oleoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine + hexa-acyl lipid A
2-oleoyl-sn-glycero-3-phosphoethanolamine + hepta-acyl lipid A
1-palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
1-palmitoyl-2-palmitoyl-sn-glycero-3-phosphoserine + hexa-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphoserine + hepta-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
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-
-
?
1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
2-acyl-sn-glycero-3-phosphocholine + lipid X
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + 3-O-deacyl lipid X
2-acyl-sn-glycero-3-phosphocholine + lipid X
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + 3-O-deacyl lipid X
2-acyl-sn-glycero-3-phosphocholine + lipid X
-
-
-
?
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
2-acyl-sn-glycero-3-phosphocholine + lipid IVB
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA
2-acyl-sn-glycero-3-phosphocholine + lipid IVB
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA
2-acyl-sn-glycero-3-phosphocholine + lipid IVB
-
-
-
?
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA
2-acyl-sn-glycero-3-phosphocholine + lipid IVB
-
-
-
?
2-oleoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-oleoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
2-oleoyl-sn-glycero-3-phosphoethanolamine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine + hexa-acyl lipid A
2-oleoyl-sn-glycero-3-phosphoethanolamine + hepta-acyl lipid A
-
-
-
?
2-palmitoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
-
-
-
?
2-palmitoyl-sn-glycero-3-phosphoserine + hepta-acyl lipid A
-
-
-
?
1-palmitoyl-2-palmitoyl-sn-glycero-3-phosphoserine + hexa-acyl lipid A
2-palmitoyl-sn-glycero-3-phosphoserine + hepta-acyl lipid A
-
-
-
?
?
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enzyme from Bordetella bronchiseptica transfers palmitates to the lipid A C-3' positions
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-
?
additional information
?
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enzyme from Bordetella bronchiseptica transfers palmitates to the lipid A C-3' positions
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-
?
additional information
?
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enzyme from Bordetella parapertussis transfers palmitates to the lipid A C-2 and C-3' positions
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-
?
additional information
?
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PagP transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors with a strong preference for palmitate in the sn1 position. No substrates: sn-1-palmitoyl-2-lyso-phosphatidylcholine or the sn-2/sn-3 isomer of dipalmitoyl phosphatidylcholine
-
-
?
additional information
?
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PagP measures the palmitoyl group with an internal hydrocarbon ruler that is formed in the interior of the eightstranded antiparallel beta barrel. Phospholipid access occurs at the crenel present between strands F and G so the phospholipid head group can remain exposed to the cell exterior while the lipid acyl chain remains in a predominantly hydrophobic environment as it translocates to the protein interior
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-
?
additional information
?
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enzyme from Pseudomonas aeruginosa transfers palmitates to the lipid A C-3' positions
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-
?
additional information
?
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enzyme from Pseudomonas aeruginosa transfers palmitates to the lipid A C-3' positions
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-
?
additional information
?
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PagP transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors with a strong preference for palmitate in the sn1 position. No substrates: sn-1-palmitoyl-2-lyso-phosphatidylcholine or the sn-2/sn-3 isomer of dipalmitoyl phosphatidylcholine
-
-
?
additional information
?
-
PagP transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors with a strong preference for palmitate in the sn1 position. No substrates: sn-1-palmitoyl-2-lyso-phosphatidylcholine or the sn-2/sn-3 isomer of dipalmitoyl phosphatidylcholine
-
-
?