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2.3.1.250: [Wnt protein] O-palmitoleoyl transferase

This is an abbreviated version!
For detailed information about [Wnt protein] O-palmitoleoyl transferase, go to the full flat file.

Word Map on EC 2.3.1.250

Reaction

(9Z)-hexadec-9-enoyl-CoA
+
[Wnt]-L-serine
=
CoA
+
[Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine

Synonyms

CG6205, MG61, Mom-1, Mporc, mPorcD, PORC, PORCN, porcupine, PPN, protein-serine O-palmitoleoyltransferase porcupine, Xporc

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.250 [Wnt protein] O-palmitoleoyl transferase

Cloned

Cloned on EC 2.3.1.250 - [Wnt protein] O-palmitoleoyl transferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene MG61, DNA and amino acid sequence determination and analysis, sequence comparisons
gene mom-1, DNA and amino acid sequence determination and analysis, sequence comparisons
gene Porc, DNA and amino acid sequence determination and analysis, sequence comparisons, recombinant expression in HEK-293 cells with or without co-expression of Wg
gene porc, expression of the enzyme tagged with three HA epitopes at amino acid 28. Capped porc, porc3HA28, DELTA34, DELTA66, and DELTA110 RNA are prepared by in vitro transcription and RNA is injected into Drosophila embryos
gene PORCN, DNA and amino acid sequence determination and analysis, genotyping
gene PORCN, quantitative PCR enzyme expression analysis
gene PORCN, quantitative RT-PCR enzyme expression analysis. PORCN splice variants differ globally in signaling activity in HT-1080 cells
gene Xporc, DNA and amino acid sequence determination and analysis, sequence comparisons
overexpression of HA-tagged human PORC to confirm the ability of hPORC RNAi constructs to knockdown hPORC expression
single gene Mporc, variants by alternative splicing, DNA and amino acid sequence determination and analysis, sequence comparisons, co-expression in COS-1 cells of HA-tagged Mporc and either Myc-tagged Wnt or partial laminin beta chain, recombinant expression in HEK-293 cells with or without co-expression of Drosophila melanogaster Wnt variant Wg