2.3.1.244: 2-methylbutanoate polyketide synthase

This is an abbreviated version, for detailed information about 2-methylbutanoate polyketide synthase, go to the full flat file.

Reaction

acetyl-CoA
+
malonyl-CoA
+
[2-methylbutanoate polyketide synthase]
+ 2 NADPH + 2 H+ +
S-adenosyl-L-methionine
=
(S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase]
+ 2 CoA +
CO2
+ 2 NADP+ +
S-adenosyl-L-homocysteine
+
H2O

Synonyms

LDKS, LocF, lovastatin diketide synthase, LovF

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.244 2-methylbutanoate polyketide synthase