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2.3.1.239: 10-deoxymethynolide synthase

This is an abbreviated version!
For detailed information about 10-deoxymethynolide synthase, go to the full flat file.

Word Map on EC 2.3.1.239

Reaction

malonyl-CoA
+ 5 (2S)-methylmalonyl-CoA + 5 NADPH + 5 H+ =
10-deoxymethynolide
 + 6 CoA + 6 CO2 + 5 NADP+ + 2 H2O

Synonyms

methymycin/picromycin polyketide synthase, picromycin/methymycin PKS, picromycin/methymycin polyketide synthase, PICS, PikAI, PikAIII, PikAIV, pikromycin PKS, pikromycin polyketide synthase, type I polyketide synthase PikAIV

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.239 10-deoxymethynolide synthase

Natural Substrates Products

Natural Substrates Products on EC 2.3.1.239 - 10-deoxymethynolide synthase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
malonyl-CoA + 5 (2S)-methylmalonyl-CoA + 5 NADPH + 5 H+
10-deoxymethynolide + 6 CoA + 6 CO2 + 5 NADP+ + 2 H2O
show the reaction diagram
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the product 10-deoxymethynolide is an intermediate in the biosynthesis of methymycin
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