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2.3.1.237: neocarzinostatin naphthoate synthase

This is an abbreviated version!
For detailed information about neocarzinostatin naphthoate synthase, go to the full flat file.

Reaction

acetyl-CoA
+ 5 malonyl-CoA + 2 NADPH + 2 H+ =
2-hydroxy-5-methyl-1-naphthoate
+ 6 CoA + 5 CO2 + 3 H2O + 2 NADP+

Synonyms

naphthoic acid synthase, ncsB, NNS

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.237 neocarzinostatin naphthoate synthase

Substrates Products

Substrates Products on EC 2.3.1.237 - neocarzinostatin naphthoate synthase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + 5 malonyl-CoA + 2 NADPH + 2 H+
2-hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+
show the reaction diagram