2.3.1.225: protein S-acyltransferase
This is an abbreviated version!
For detailed information about protein S-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.225
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2.3.1.225
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palmitoylation
-
palmitate
-
s-acylation
-
huntingtin
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palmitoylation-dependent
-
huntingtin-interacting
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2-bromopalmitate
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s-acyltransferases
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medicine
-
autoacylation
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16-carbon
-
snap25
-
acyl-acyl
-
palmitoylation-deficient
- 2.3.1.225
-
palmitoylation
- palmitate
-
s-acylation
- huntingtin
-
palmitoylation-dependent
-
huntingtin-interacting
- 2-bromopalmitate
-
s-acyltransferases
- medicine
-
autoacylation
-
16-carbon
- snap25
-
acyl-acyl
-
palmitoylation-deficient
Reaction
Synonyms
Akr1, Akr1p, APT1, Asp-His-His-Cys motif palmitoyl transferase, At3g51390, DHHC palmitoyl transferase, DHHC protein, DHHC protein acyltransferase, DHHC-2, DHHC-21, DHHC-21 palmitoyl transferase, DHHC-3, DHHC-3 palmitoyl transferase, DHHC-7, DHHC-8, DHHC-CRD S-acyltransferase, DHHC16, DHHC17, DHHC2, DHHC3, DHHC4, DHHC5, Erf2, Erf2p, G-protein palmitoyltransferase, HIP14, palmitoyl acyltransferase, Pat, PAT10, PAT14, PAT15, PAT21, PAT24, PAT4, Pfa3, Pfa4, PFA5, protein acyl transferase, protein acyltransferase, protein S-acyl transferase 4, Ras PAT, S-protein acyltransferase, SEC18p, Swf1, ZDHHC3, ZDHHC5
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2.3.1.225 protein S-acyltransferaseAdvanced search results
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Reference on EC 2.3.1.225 - protein S-acyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Li, Y.; Hu, J.; Hoefer, K.; Wong, A.M.; Cooper, J.D.; Birnbaum, S.G.; Hammer, R.E.; Hofmann, S.L.
DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory
J. Biol. Chem.
285
13022-13031
2010
Mus musculus (Q8VDZ4)
Linder, M. E.; Deschenes, R. J.
New insights into the mechanisms of protein palmitoylation
Biochemistry
42
4311-4320
2003
Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens, Rattus norvegicus
Veit, M.; Sachs, K.; Heckelmann, M.; Maretzki, D.; Hofmann, K. P.; Schmidt, M. F. G.
Palmitoylation of rhodopsin with S-protein acyltransferase: enzyme catalyzed reaction versus autocatalytic acylation
Biochim. Biophys. Acta
1394
90-98
1998
Bos taurus
Dunphy, J.T.; Schroeder, H.; Leventis, R.; Greentree, W.K; Knudsen, J.K.; Silvius, J.R.; Linder, M.E.
Differential effects of acyl-CoA binding protein on enzymatic and non-enzymatic thioacylation of protein and peptide substrates
Biochim. Biophys. Acta
1485
185-198
2000
Chlorocebus aethiops, Bos taurus
Veit, M.; Dietrich, L.E.P.; Ungermann, C.
Biochemical characterization of the vacuolar palmitoyl acyltransferase
FEBS Lett.
540
101-105
2003
Saccharomyces cerevisiae, Saccharomyces cerevisiae BJ3505
Dunphy, J. T.; Greentree, W. K.; Manahan, C. L.; Linder, M. E.
G-protein palmitoyltransferase activity is enriched in plasma membranes
J. Biol. Chem.
271
7154-7159
1996
Bos taurus, Rattus norvegicus
Dunphy, J. T.; Greentree, W. K.; Linder, M. E.
Enrichment of G-protein palmitoyltransferase activity in low density membranes
J. Biol. Chem.
276
43300-43304
2001
Bos taurus
Jennings, B. C.; Linder, M. E.
DHHC protein S-acyltransferases use similar ping-pong kinetic mechanisms but display different acyl-CoA specificities
J. Biol. Chem.
287
7236-7245
2012
Homo sapiens, Mus musculus (Q8R173)
Fernandez-Hernando, C.; Fukata, M.; Bernatchez, P. N.; Fukata, Y.; Lin, M. I.; Bredt, D. S.; Sessa, W. C.
Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase
J. Cell. Biol.
174
369-377
2006
Homo sapiens
Mitchell, D. A.; Vasudevan, A.; Linder, M. E.; Deschenes, R. J.
Protein palmitoylation by a family of DHHC protein S-acyltransferases
J. Lipid Res.
47
1118-1127
2006
Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens, Homo sapiens (Q8IUH5), Homo sapiens (Q9Y397)
Zeidman, R.; Buckland, G.; Cebecauer, M.; Eissmann, P.; Davis, D.M.; Magee, A.I.
DHHC2 is a protein S-acyltransferase for Lck
Mol. Membr. Biol.
28
473-486
2011
Homo sapiens (Q969W1), Homo sapiens (Q9NPG8), Homo sapiens (Q9UIJ5)
Hemsley, P. A.; Kemp, A. C.; Grierson, C. S.
The TIP GROWTH DEFECTIVE1 S-acyl transferase regulates plant cell growth in Arabidopsis
Plant Cell
17
2554-2563
2005
Arabidopsis thaliana (Q52T38)
Batistic, O.
Genomics and localization of the Arabidopsis DHHC-CRD S-acyltransferase protein family
Plant Physiol.
160
1597-1612
2012
Arabidopsis thaliana (B3DN87), Arabidopsis thaliana (O80685), Arabidopsis thaliana (Q0WQK2), Arabidopsis thaliana (Q3EBC2), Arabidopsis thaliana (Q3EC11), Arabidopsis thaliana (Q500Z2), Arabidopsis thaliana (Q52T38), Arabidopsis thaliana (Q5M757), Arabidopsis thaliana (Q6DR03), Arabidopsis thaliana (Q7XA86), Arabidopsis thaliana (Q8L5Y5), Arabidopsis thaliana (Q8VYP5), Arabidopsis thaliana (Q8VYS8), Arabidopsis thaliana (Q93VV0), Arabidopsis thaliana (Q94C49), Arabidopsis thaliana (Q9C533), Arabidopsis thaliana (Q9FLM3), Arabidopsis thaliana (Q9LIE4), Arabidopsis thaliana (Q9LIH7), Arabidopsis thaliana (Q9M115), Arabidopsis thaliana (Q9M1K5), Arabidopsis thaliana (Q9M306), Arabidopsis thaliana (Q9SB58), Arabidopsis thaliana
Zhou, L.Z.; Li, S.; Feng, Q.N.; Zhang, Y.L.; Zhao, X.; Zeng, Y.L.; Wang, H.; Jiang, L.; Zhang, Y.
Protein S-acyl transferase10 is critical for development and salt tolerance in Arabidopsis
Plant Cell
25
1093-1107
2013
Arabidopsis thaliana (Q7XA86), Arabidopsis thaliana
Zhang, Y.L.; Li, E.; Feng, Q.N.; Zhao, X.Y.; Ge, F.R.; Zhang, Y.; Li, S.
Protein palmitoylation is critical for the polar growth of root hairs in Arabidopsis
BMC Plant Biol.
15
50
2015
Arabidopsis thaliana (Q52T38), Arabidopsis thaliana (Q7XA86)
Gonzalez Montoro, A.; Chumpen Ramirez, S.; Valdez Taubas, J.
The canonical DHHC motif is not absolutely required for the activity of the yeast S-acyltransferases Swf1 and Pfa4
J. Biol. Chem.
290
22448-22459
2015
Saccharomyces cerevisiae (Q04629), Saccharomyces cerevisiae (Q12006)
Gottlieb, C.D.; Zhang, S.; Linder, M.E.
The cysteine-rich domain of the DHHC3 palmitoyltransferase is palmitoylated and contains tightly bound zinc
J. Biol. Chem.
290
29259-29269
2015
Mus musculus (Q8R173)
Qi, B.; Doughty, J.; Hooley, R.
A Golgi and tonoplast localized S-acyl transferase is involved in cell expansion, cell division, vascular patterning and fertility in Arabidopsis
New Phytol.
200
444-456
2013
Arabidopsis thaliana (Q7XA86)
Li, Y.; Scott, R.; Doughty, J.; Grant, M.; Qi, B.
Protein S-acyltransferase 14: a specific role for palmitoylation in leaf senescence in Arabidopsis
Plant Physiol.
170
415-428
2016
Arabidopsis thaliana (Q8VYP5)
Howie, J.; Reilly, L.; Fraser, N.J.; Vlachaki Walker, J.M.; Wypijewski, K.J.; Ashford, M.L.; Calaghan, S.C.; McClafferty, H.; Tian, L.; Shipston, M.J.; Boguslavskyi, A.; Shattock, M.J.; Fuller, W.
Substrate recognition by the cell surface palmitoyl transferase DHHC5
Proc. Natl. Acad. Sci. USA
111
17534-17539
2014
Rattus norvegicus (Q2THW7), Mus musculus (Q8VDZ4)
Zhao, X.Y.; Wang, J.G.; Song, S.J.; Wang, Q.; Kang, H.; Zhang, Y.; Li, S.
Precocious leaf senescence by functional loss of PROTEIN S-ACYL TRANSFERASE14 involves the NPR1-dependent salicylic acid signaling
Sci. Rep.
6
20309
2016
Arabidopsis thaliana (Q8VYP5)
Sharma, C.; Wang, H.X.; Li, Q.; Knoblich, K.; Reisenbichler, E.S.; Richardson, A.L.; Hemler, M.E.
Protein acyltransferase DHHC3 regulates breast tumor growth, oxidative stress, and senescence
Cancer Res.
77
6880-6890
2017
Homo sapiens (Q9NYG2), Homo sapiens
Ko, P.J.; Woodrow, C.; Dubreuil, M.M.; Martin, B.R.; Skouta, R.; Bassik, M.C.; Dixon, S.J.
A ZDHHC5-GOLGA7 protein acyltransferase complex promotes nonapoptotic cell death
Cell Chem. Biol.
26
1716-1724
2019
Homo sapiens (Q9C0B5)
Li, Y.; Qi, B.
Progress toward understanding protein S-acylation Prospective in plants
Front. Plant Sci.
8
346
2017
Saccharomyces cerevisiae (P39010), Saccharomyces cerevisiae (P42836), Saccharomyces cerevisiae (Q03289), Saccharomyces cerevisiae (Q04629), Saccharomyces cerevisiae (Q06551), Saccharomyces cerevisiae (Q12006), Saccharomyces cerevisiae ATCC 204508 (P39010), Saccharomyces cerevisiae ATCC 204508 (P42836), Saccharomyces cerevisiae ATCC 204508 (Q03289), Saccharomyces cerevisiae ATCC 204508 (Q04629), Saccharomyces cerevisiae ATCC 204508 (Q06551), Saccharomyces cerevisiae ATCC 204508 (Q12006)
Li, Y.; Xu, J.; Li, G.; Wan, S.; Batistic, O.; Sun, M.; Zhang, Y.; Scott, R.; Qi, B.
Protein S-acyl transferase 15 is involved in seed triacylglycerol catabolism during early seedling growth in Arabidopsis
J. Exp. Bot.
70
5205-5216
2019
Arabidopsis thaliana (Q500Z2)
Quiroga, R.; Valdez Taubas, J.
Bioinformatic identification of functionally and structurally relevant residues and motifs in protein S-acyltransferases
Methods Mol. Biol.
2009
191-199
2019
Giardia intestinalis (V6U0K4)
Li, Y.; Li, H.J.; Morgan, C.; Bomblies, K.; Yang, W.; Qi, B.
Both male and female gametogenesis require a fully functional protein S-acyl transferase 21 in Arabidopsis thaliana
Plant J.
100
754-767
2019
Arabidopsis thaliana (Q6DR03)
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