2.3.1.217: curcumin synthase
This is an abbreviated version!
For detailed information about curcumin synthase, go to the full flat file.
Word Map on EC 2.3.1.217
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2.3.1.217
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curcuma
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diketide-coa
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longa
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curcuminoids
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rhizome
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turmeric
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synthesis
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polyketide
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demethoxycurcumin
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bisdemethoxycurcumin
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ferulic
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4-coumarate
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zingiberaceae
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zedoaria
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condensing
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intraspecies
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caffeoyl-coa
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kwangsiensis
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3-hydroxylase
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analysis
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biofuel production
- 2.3.1.217
- curcuma
-
diketide-coa
- longa
-
curcuminoids
- rhizome
- turmeric
- synthesis
- polyketide
- demethoxycurcumin
- bisdemethoxycurcumin
-
ferulic
- 4-coumarate
-
zingiberaceae
- zedoaria
-
condensing
-
intraspecies
- caffeoyl-coa
- kwangsiensis
-
3-hydroxylase
- analysis
- biofuel production
Reaction
Synonyms
curcumin synthase, curcumin synthase 1, curcumin synthase 2, CURS, CURS1, CURS2, CURS3, OsCUS, ZoCURS
ECTree
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General Information
General Information on EC 2.3.1.217 - curcumin synthase
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evolution
metabolism
additional information
evolution
the enzyme belongs to the Type III polyketide synthase family. A Cys-His-Asn catalytic triad is conserved in all known type III PKSs
evolution
the enzyme belongs to the type III polyketide synthase family. A Cys-His-Asn catalytic triad is conserved in all known type III polyketide synthases
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the enzyme catalyzes a step in the curcuminoid biosynthesis, pathway overview
metabolism
the enzyme catalyzes a step in the curcuminoid biosynthesis, pathway overview
active site residue His303 is important for 2-oxoacid condensation, involvement of the hydrophobic cavity around Phe265 in 2-oxoacid condensation, wild-type and mutant ligand binding structures and structure-function relationship, modeling, overview
additional information
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CURS can collaborate with curcumin synthase, DCS, EC 2.3.1.218, which provides the substrate feruloylacetyl-CoA from condensation of feruloyl-CoA and malonyl-CoA, overview