2.3.1.21: carnitine O-palmitoyltransferase

This is an abbreviated version!
For detailed information about carnitine O-palmitoyltransferase, go to the full flat file.

Word Map on EC 2.3.1.21

2.3.1.21

peroxisome

triglyceride

proliferator-activated

acyl-coas

malonyl-coa

obesity

carboxylase

adipose

high-fat

acetyl-coa

beta-oxidation

cholesterol

hepatocytes

cardiac

palmitate

sterol

lipogenesis

lipoprotein

steatosis

lipase

amp-activated

adipocytes

obese

acyltransferase

triacylglycerols

diet-induced

element-binding

etomoxir

leptin

lipogenic

lipolysis

adiponectin

pparalpha

srebp-1c

medium-chain

nafld

nonalcoholic

ketogenesis

stearoyl-coa

protein-1c

hfd-induced

rhabdomyolysis

palmitate-induced

srebf1

anti-obesity

muscle-type

myoglobinuria

lcfas

synthesis

medicine

vlcad

acaca

pharmacology

Reaction

Synonyms

acylcarnitine transferase, carnitine O-palmitoyltransferase, carnitine O-palmitoyltransferase I, carnitine palmitoyl transferase 1, carnitine palmitoyl transferase 1A, carnitine palmitoyl transferase-1A, carnitine palmitoyl transferase-I, carnitine palmitoyl-transferase-1c, carnitine palmitoyltransferae 1A, carnitine palmitoyltransferase, carnitine palmitoyltransferase 1, carnitine palmitoyltransferase 1A, carnitine palmitoyltransferase 1B, carnitine palmitoyltransferase 2, carnitine palmitoyltransferase I, carnitine palmitoyltransferase IA, carnitine palmitoyltransferase II, carnitine palmitoyltransferase-1, carnitine palmitoyltransferase-1c, carnitine palmitoyltransferase-A, carnitine palmitoyltransferase-I, carnitine palmitoyltransferases 2, CPT, CPT I, CPT IA, CPT Ialpha1a, CPT Ialpha1b, CPT Ialpha2a, CPT Ibeta, CPT II, CPT-1, CPT-2, CPT-A, CPT-B, CPT-Ialpha, CPT-IL, CPT1, CPT1-A, CPT1-B, CPT1-C, CPT1A, CPT1B, CPT1c, CPT2, CPTi, CPTI beta, CPTII, CPTo, L-carnitine palmitoyltransferase, L-CPT 1, L-CPT1, M-CPT 1, M-CPTI, muscle carnitine palmitoyltransferase I, palmitoylcarnitine transferase, palmitoyltransferase, carnitine

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.21 carnitine O-palmitoyltransferase

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Results	in table
29	Activating Compound
4324	AA Sequence
14	Application
1	CAS Registry Number
42	Cloned(Commentary)
1	Crystallization (Commentary)
3083	Disease/ Diagnostics
7	Expression
14	General Information
7	General Stability
63	IC50 Value
181	Inhibitors
22	Ki Value [mM]
200	KM Value [mM]
171	Localization
4	Metals/Ions
43	Molecular Weight [Da]
132	Natural Substrates/ Products (Substrates)
241	Organism
4	Pathway
13	PDB ID
33	pH Optimum
3	pH Range
1	pH Stability
2	pI Value
4	Posttranslational Modification
108	Protein Variants
28	Purification (Commentary)
10	Reaction
11	Reaction Type
169	Reference
3	Renatured (Commentary)
311	Source Tissue
95	Specific Activity [micromol/min/mg]
3	Storage Stability
293	Substrates and Products (Substrate)
28	Subunits
161	Synonyms
1	Systematic Name
29	Temperature Optimum [°C]
1	Temperature Stability [°C]

Molecular Weight

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of the Enzyme Summary Page.

Molecular Weight on EC 2.3.1.21 - carnitine O-palmitoyltransferase

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150000

Rattus norvegicus

CPT I and II, gel filtration

486569

20000

Pisum sativum

x * 20000, CPT I and II, SDS-PAGE

486583

260000

Gallus gallus

mitochondria, gel filtration

274000

gel filtration

280000 - 320000

gel filtration

30000

x * 30000, SDS-PAGE

430000

CPTo and CPTi, gel filtration

62500

1 * 62500, SDS-PAGE

63000

gel filtration

63500

gel filtration, sucrose density gradient sedimentation

486528

64000

Gallus gallus

1 * 64000, peroxisomes, SDS-PAGE

486549

66000

4 entries

660000

Bos taurus

about, gel filtration

67000

68000

69000

4 * 69000, mitochondria

69200

x * 69200, SDS-PAGE

70000

x * 70000, recombinant CPT II, SDS-PAGE

486576

75000

Rattus norvegicus

determined by SDS-PAGE and Western Blot analysis

686125

82000

2 entries

82900

Megalobrama amblycephala

A0A0A7ECG5

x * 82900, calculated from amino acid sequence

735980

86000

2 entries

88000

Rattus norvegicus

x * 88000, recombinant CPT I, SDS-PAGE

486576

88200

Homo sapiens

x * 88200, isozymes L-CPT1 and M-CPT1

673216

90200

Rattus norvegicus

x * 90200, estimated from SDS-PAGE

735458

94000

Rattus norvegicus

1 * 94000, liver, SDS-PAGE

486566

additional information

9 entries