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2.3.1.21: carnitine O-palmitoyltransferase

This is an abbreviated version!
For detailed information about carnitine O-palmitoyltransferase, go to the full flat file.

Word Map on EC 2.3.1.21

Reaction

palmitoyl-CoA
+
L-carnitine
=
CoA
 +
L-palmitoylcarnitine

Synonyms

acylcarnitine transferase, carnitine O-palmitoyltransferase, carnitine O-palmitoyltransferase I, carnitine palmitoyl transferase 1, carnitine palmitoyl transferase 1A, carnitine palmitoyl transferase-1A, carnitine palmitoyl transferase-I, carnitine palmitoyl-transferase-1c, carnitine palmitoyltransferae 1A, carnitine palmitoyltransferase, carnitine palmitoyltransferase 1, carnitine palmitoyltransferase 1A, carnitine palmitoyltransferase 1B, carnitine palmitoyltransferase 2, carnitine palmitoyltransferase I, carnitine palmitoyltransferase IA, carnitine palmitoyltransferase II, carnitine palmitoyltransferase-1, carnitine palmitoyltransferase-1c, carnitine palmitoyltransferase-A, carnitine palmitoyltransferase-I, carnitine palmitoyltransferases 2, CPT, CPT I, CPT IA, CPT Ialpha1a, CPT Ialpha1b, CPT Ialpha2a, CPT Ibeta, CPT II, CPT-1, CPT-2, CPT-A, CPT-B, CPT-Ialpha, CPT-IL, CPT1, CPT1-A, CPT1-B, CPT1-C, CPT1A, CPT1B, CPT1c, CPT2, CPTi, CPTI beta, CPTII, CPTo, L-carnitine palmitoyltransferase, L-CPT 1, L-CPT1, M-CPT 1, M-CPTI, muscle carnitine palmitoyltransferase I, palmitoylcarnitine transferase, palmitoyltransferase, carnitine

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.21 carnitine O-palmitoyltransferase

Expression

Expression on EC 2.3.1.21 - carnitine O-palmitoyltransferase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
a high fat diet with 15% fat can decrease the expression of the enzyme
CPT I activity is the highest at 1-month old grass carp, nearly 2fold higher than that at hatching
-
Cpt1A mRNA expression dramatically increases and activity remains unchanged after fasting
isoform CPT1C can be induced by hypoxia or glucose deprivation and is regulated by AMPKalpha
isoform CPT1C expression is frequently up-regulated in human lung tumors. CPT1C can be induced by hypoxia or glucose deprivation and is regulated by AMPKalpha
mitochondrial CPT1 proteins are targeted for inactivation by diverse oxidants or oxidative stress in human cells
-
mRNA expression significantly increases at 24 h post-feeding in liver and heart