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2.3.1.207: beta-ketodecanoyl-[acyl-carrier-protein] synthase

This is an abbreviated version!
For detailed information about beta-ketodecanoyl-[acyl-carrier-protein] synthase, go to the full flat file.

Reaction

octanoyl-CoA
+
a malonyl-[acyl-carrier protein]
=
a 3-oxodecanoyl-[acyl-carrier protein]
+
CoA
+
CO2

Synonyms

beta-ketoacyl synthase, FabY, PA3286 protein

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.207 beta-ketodecanoyl-[acyl-carrier-protein] synthase

Systematic Name

Systematic Name on EC 2.3.1.207 - beta-ketodecanoyl-[acyl-carrier-protein] synthase

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SYSTEMATIC NAME
IUBMB Comments
octanoyl-CoA:malonyl-[acyl-carrier protein] C-heptanoylltransferase (decarboxylating, CoA-forming)
This enzyme, which has been characterized from the bacterium Pseudomonas aeruginosa PAO1, catalyses the condensation of octanoyl-CoA, obtained from exogenously supplied fatty acids via beta-oxidation, with malonyl-[acp], forming 3-oxodecanoyl-[acp], an intermediate of the fatty acid elongation cycle. The enzyme provides a shunt for beta-oxidation degradation intermediates into de novo fatty acid biosynthesis.