2.3.1.192: glycine N-phenylacetyltransferase
This is an abbreviated version!
For detailed information about glycine N-phenylacetyltransferase, go to the full flat file.
Reaction
Synonyms
AAC, arylacetyl acyl-CoA:amino acid N-acyltransferase, arylacetyl-CoA N-acyltransferase, arylacetyltransferase, GAT, phenylacetyltransferase
ECTree
2.3.1.192 glycine N-phenylacetyltransferaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.3.1.192 - glycine N-phenylacetyltransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1-naphthylacetyl-CoA + glycine
1-naphthylacetylglycine + CoA
-
best substrate
-
-
?
1-naphtylacetyl-CoA + L-glutamine
? + CoA
-
3-5% of the rate with phenacetyl-CoA
-
-
?
2,4-dichlorophenoxyacetyl-CoA + glycine
2,4-dichlorophenoxyacetylglycine + CoA
-
-
-
-
?
indoleacetyl-CoA + L-glutamine
? + CoA
-
3-5% of the rate with phenacetyl-CoA
-
-
?
phenoxyacetyl-CoA + glycine
phenoxyacetylglycine + CoA
-
overall rate of conjugation of the phenoxyherbicides are slow relative to the standard substrate phenylacetyl-CoA
-
-
?
phenylacetyl-CoA + L-asparagine
? + CoA
-
stereospecific for the L-isomer of asparagine
-
-
?
phenylacetyl-CoA + L-glutamine
phenylacetyl-L-glutamine + CoA
-
may substitue for glycine, but at lower rate
-
-
?
phenylacetyl-CoA + glycine
phenylacetylglycine + CoA
-
glycine is the preferred acceptor
-
-
?
phenylacetyl-CoA + L-glutamine
? + CoA
-
stereospecific for the L-isomer of glutamine
-
-
?
additional information
?
-
-
arginine and glutamine can substitute for glycine in the phenylacetyl-CoA assay and, while the rates are lower, they are equivalently affected by salt. No substrate: benzoyl-CoA, butyryl-CoA, and salicyl-CoA
-
-
?
additional information
?
-
-
glycination of phenylacetyl-CoA by human phenacetyltransferase can only be detected at a concentration of glycine above 50 mM, and the rates are below 2% of the rate of glutamination
-
-
?
