2.3.1.191: UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase
This is an abbreviated version!
For detailed information about UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.191
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2.3.1.191
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acyltransferases
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lps
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francisella
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trachomatis
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chlamydia
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lipopolysaccharide
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udp-n-acetylglucosamine
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homotrimer
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drug development
- 2.3.1.191
- acyltransferases
- lps
- francisella
- trachomatis
-
chlamydia
- lipopolysaccharide
- udp-n-acetylglucosamine
-
homotrimer
- drug development
Reaction
Synonyms
acyl-ACP:UDP-3-O-(3-hydroxyacyl)-GlcN N-acyltransferase, acyltransferase LpxD, CtLpxD, EcLpxD, firA, La0512, LpxD, LpxD1, Lpxd2, PA3646, UDP-3-O-(R-3-hydroxyacyl)-glucosamine acyltransferase, UDP-3-O-acyl-glucosamine N-acyltransferase
ECTree
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Systematic Name
Systematic Name on EC 2.3.1.191 - UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase
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(3R)-3-hydroxyacyl-[acyl-carrier protein]:UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine N-acyltransferase
The enzyme catalyses a step of lipid A biosynthesis. LpxD from Escherichia coli prefers (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] [3], but it does not have an absolute specificity for 14-carbon hydroxy fatty acids, as it can transfer other fatty acids, including odd-chain fatty acids, if they are available to the organism [5].