2.3.1.191: UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase

This is an abbreviated version!
For detailed information about UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.191

2.3.1.191

acyltransferases

lps

francisella

trachomatis

chlamydia

lipopolysaccharide

udp-n-acetylglucosamine

homotrimer

drug development

Reaction

a (3R)-3-hydroxyacyl-[acyl-carrier protein]

a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine

a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine

Synonyms

acyl-ACP:UDP-3-O-(3-hydroxyacyl)-GlcN N-acyltransferase, acyltransferase LpxD, CtLpxD, EcLpxD, firA, La0512, LpxD, LpxD1, Lpxd2, PA3646, UDP-3-O-(R-3-hydroxyacyl)-glucosamine acyltransferase, UDP-3-O-acyl-glucosamine N-acyltransferase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.191 UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase

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Results	in table
1	Activating Compound
23563	AA Sequence
1	Application
14	Cloned(Commentary)
6	Crystallization (Commentary)
22	General Information
2	IC50 Value
11	Inhibitors
11	kcat/KM [mM/s]
7	Ki Value [mM]
25	KM Value [mM]
2	Localization
3	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
33	Organism
11	Pathway
45	PDB ID
2	pH Optimum
16	Protein Variants
7	Purification (Commentary)
1	Reaction
29	Reference
2	Source Tissue
2	Specific Activity [micromol/min/mg]
21	Substrates and Products (Substrate)
4	Subunits
32	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
24	Turnover Number [1/s]

Purification

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Purification on EC 2.3.1.191 - UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase

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3 entries

partial

Escherichia coli

698693

purification of untagged EcLpxD and an active N-terminally His6-tagged LpxD variant to near homogeneityrecombinant enzyme

Escherichia coli

696264

recombinant His6-tagged LpxD from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and gel filtration

Escherichia coli

718571

recombinant N-terminally His6-tagged LpxD from Escherichia coli strain BL21 (DE3) by nickel affinity chromatography and gel filtration

Pseudomonas aeruginosa

Q9HXY6

718513