2.3.1.185: tropine acyltransferase

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For detailed information about tropine acyltransferase, go to the full flat file.

Reaction

Synonyms

acetyI-CoA:tropine acyltransferase, acetyl-CoA:tropine transferase, tropine:acyl-CoA transferase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.185 tropine acyltransferase

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Results	in table
2	Activating Compound
2	CAS Registry Number
2	KM Value [mM]
10	Organism
3	Pathway
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
9	Reference
2	Source Tissue
3	Specific Activity [micromol/min/mg]
25	Substrates and Products (Substrate)
8	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.3.1.185 - tropine acyltransferase

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SYSTEMATIC NAME

IUBMB Comments

acyl-CoA:tropine O-acyltransferase

This enzyme exhibits absolute specificity for the endo/3alpha configuration found in tropine as pseudotropine (tropan-3beta-ol; see EC 2.3.1.186, pseudotropine acyltransferase) is not a substrate [3]. Acts on a wide range of aliphatic acyl-CoA derivatives, with tigloyl-CoA and acetyl-CoA being the best substrates. It is probably involved in the formation of the tropane alkaloid littorine, which is a precursor of hyoscyamine [4].