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2.3.1.184: acyl-homoserine-lactone synthase

This is an abbreviated version!
For detailed information about acyl-homoserine-lactone synthase, go to the full flat file.

Word Map on EC 2.3.1.184

Reaction

an acyl-[acyl-carrier protein]
+
S-adenosyl-L-methionine
=
an [acyl-carrier protein]
 +
S-methyl-5'-thioadenosine
 +
an N-acyl-L-homoserine lactone

Synonyms

3-oxo-C12-HSL synthase, AbaI, ACII, acyl homoserine lactone synthase, acyl-homoserine lactone synthase, acyl-homoserine-lactone synthase, acyl-homoserinelactone synthase, acyl-HSL synthase, acylhomoserine lactone synthase, AHL synthase, AHS, AHSL synthase, AhyI, AinS, AinS protein, AurI, autoinducer synthase, autoinducer synthesis protein rhlI, C4-HSL synthase, C6-AHL synthase, CsaI, EsaI, ExpI, expIEcz, ExpISCC1, ExpISCC3065, hdtS, HHL synthase, LasI, LasI synthase, LasI/R, LasR, LuxI, LuxI protein, LuxM, More, MrlI1, MrlI2, MrtI, mtqI, N-acyl homoserine lactone synthase, N-acyl-homoserine lactone synthase, N-hexanoyl homoserine lactone synthase, NmuI, Nmul_A2390, PgaI, PhzI, PppuI, PsyI, RhlI, RhlI/R, signal synthase CviI, SmaI, SpnI, TofI, TraI, YenI, YpeRI, YspI, YspRI

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.184 acyl-homoserine-lactone synthase

Substrates Products

Substrates Products on EC 2.3.1.184 - acyl-homoserine-lactone synthase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-hydroxydecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-hydroxydecanoyl-L-homoserine lactone
show the reaction diagram
3-hydroxydodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-(3-hydroxydodecanoyl)-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
3-oxo-dodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxododecanoyl-L-homoserine lactone
show the reaction diagram
3-oxo-octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + 3-oxo-octanoyl-L-homoserine lactone
show the reaction diagram
3-oxododecanoyl-[acyl carrier protein] + S-adenosyl-L-methionine
N-(3-oxododecanoyl)-homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine
show the reaction diagram
3-oxododecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-(3-oxododecanoyl)-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
3-oxododecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxododecanoyl-L-homoserine lactone
show the reaction diagram
-
LasI
-
-
?
3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone
show the reaction diagram
3-oxotetradecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-(3-oxotetradecanoyl)-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
-
-
-
?
an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine
an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone
show the reaction diagram
an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone
show the reaction diagram
butanoyl [acyl carrier protein] + S-adenosyl-L-methionine
N-butanoyl homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine
show the reaction diagram
butanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-butanoyl-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
butanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + butanoyl-L-homoserine lactone
show the reaction diagram
-
RhlI
-
-
?
butyryl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-butanoyl-L-homoserine lactone
show the reaction diagram
decanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-decanoyl-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
-
-
-
?
dodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-dodecanoyl-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
-
-
-
?
hexanoyl [acyl carrier protein] + S-adenosyl-L-methionine
N-hexanoyl homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine
show the reaction diagram
-
production is only 1/15 of N-butanoyl homoserine lactone
-
-
ir
hexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-hexanoyl -L-homoserine lactone
show the reaction diagram
-
-
-
-
?
N-butanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-butanoyl-L-homoserine lactone
show the reaction diagram
N-decanoyl -[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-decanoyl -L-homoserine lactone
show the reaction diagram
-
-
-
-
?
N-hexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-hexanoyl-L-homoserine lactone
show the reaction diagram
octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-octanoyl-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
-
-
-
?
octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-octanoyl-L-homoserine lactone
show the reaction diagram
S-adenosyl-L-methionine + 3-hydroxybutyryl-[acyl-carrier protein]
5'-methylthioadenosine + N-3-hydroxybutyryl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
-
substrate of LuxM
-
-
?
S-adenosyl-L-methionine + 3-oxodecanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-3-oxodecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
S-adenosyl-L-methionine + 3-oxododecanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-3-oxododecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
S-adenosyl-L-methionine + 3-oxohexanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-3-oxohexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
S-adenosyl-L-methionine + 3-oxooctanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-3-oxooctanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
S-adenosyl-L-methionine + 3-oxotetradecanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-3-oxotetradecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
-
substrate of wild-type and mutant LasI, overview
-
-
?
S-adenosyl-L-methionine + 3-oxoundecanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-3-oxoundecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
-
substrate of wild-type and mutant LasI, overview
-
-
?
S-adenosyl-L-methionine + butyryl-CoA
5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + CoA
show the reaction diagram
S-adenosyl-L-methionine + butyryl-S-adenosyl-L-methionine
5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + S-adenosyl-L-methionine
show the reaction diagram
-
-
-
-
?
S-adenosyl-L-methionine + butyryl-[acyl-carrier protein 1]
5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein 1]
show the reaction diagram
-
substrate of RhlI, three different [acyl-carrier-protein] isozymes from Pseudomonas aeruginosa serve as substrates
-
-
?
S-adenosyl-L-methionine + butyryl-[acyl-carrier protein 2]
5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein 2]
show the reaction diagram
-
substrate of RhlI, three different [acyl-carrier-protein] isozymes from Pseudomonas aeruginosa serve as substrates
-
-
?
S-adenosyl-L-methionine + butyryl-[acyl-carrier protein 3]
5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein 3]
show the reaction diagram
-
substrate of RhlI, three different [acyl-carrier-protein] isozymes from Pseudomonas aeruginosa serve as substrates, very low activity with ACP3
-
-
?
S-adenosyl-L-methionine + butyryl-[acyl-carrier protein]
5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
S-adenosyl-L-methionine + decanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-decanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
S-adenosyl-L-methionine + hexanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-hexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
S-adenosyl-L-methionine + octanoyl-CoA
5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + CoA
show the reaction diagram
-
substrate of recombinant MBP-AinS, lower activity
-
-
?
S-adenosyl-L-methionine + octanoyl-[acyl-carrier protein]
5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
show the reaction diagram
tetradecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine
N-tetradecanoyl-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
show the reaction diagram
-
-
-
?
additional information
?
-