2.3.1.184: acyl-homoserine-lactone synthase

This is an abbreviated version!
For detailed information about acyl-homoserine-lactone synthase, go to the full flat file.

Reaction

Synonyms

3-oxo-C12-HSL synthase, AbaI, ACII, acyl homoserine lactone synthase, acyl-homoserine lactone synthase, acyl-homoserine-lactone synthase, acyl-homoserinelactone synthase, acyl-HSL synthase, acylhomoserine lactone synthase, AHL synthase, AHS, AHSL synthase, AhyI, AinS, AinS protein, AurI, autoinducer synthase, autoinducer synthesis protein rhlI, C4-HSL synthase, C6-AHL synthase, CsaI, EsaI, ExpI, expIEcz, ExpISCC1, ExpISCC3065, hdtS, HHL synthase, LasI, LasI synthase, LasI/R, LasR, LuxI, LuxI protein, LuxM, More, MrlI1, MrlI2, MrtI, mtqI, N-acyl homoserine lactone synthase, N-acyl-homoserine lactone synthase, N-hexanoyl homoserine lactone synthase, NmuI, Nmul_A2390, PgaI, PhzI, PppuI, PsyI, RhlI, RhlI/R, signal synthase CviI, SmaI, SpnI, TofI, TraI, YenI, YpeRI, YspI, YspRI

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.184 acyl-homoserine-lactone synthase

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Results	in table
4	Activating Compound
6328	AA Sequence
5	Application
1	CAS Registry Number
27	Cloned(Commentary)
4	Crystallization (Commentary)
10	Expression
66	General Information
26	Inhibitors
19	KM Value [mM]
1	Metals/Ions
3	Molecular Weight [Da]
85	Natural Substrates/ Products (Substrates)
84	Organism
3	Pathway
1	PDB ID
4	pH Optimum
3	pH Range
1	pI Value
49	Protein Variants
7	Purification (Commentary)
9	Reaction
72	Reference
3	Specific Activity [micromol/min/mg]
137	Substrates and Products (Substrate)
5	Subunits
158	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
4	Turnover Number [1/s]

Natural Substrates Products

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of the Enzyme Summary Page.

Natural Substrates Products on EC 2.3.1.184 - acyl-homoserine-lactone synthase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

3-hydroxydecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-hydroxydecanoyl-L-homoserine lactone

2 entries

3-oxo-dodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxododecanoyl-L-homoserine lactone

3 entries

3-oxo-octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + 3-oxo-octanoyl-L-homoserine lactone

Agrobacterium tumefaciens

-

TraI synthesizes primarily 3-oxo-octanoyl homoserine lactone

720492

-

-

?

3-oxododecanoyl-[acyl carrier protein] + S-adenosyl-L-methionine

N-(3-oxododecanoyl)-homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

2 entries

3-oxododecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxododecanoyl-L-homoserine lactone

Pseudomonas aeruginosa

-

LasI

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

10 entries

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

7 entries

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

10 entries

butanoyl [acyl carrier protein] + S-adenosyl-L-methionine

N-butanoyl homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

3 entries

butanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + butanoyl-L-homoserine lactone

Pseudomonas aeruginosa

-

RhlI

720492

-

-

?

hexanoyl [acyl carrier protein] + S-adenosyl-L-methionine

N-hexanoyl homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

Pseudomonas aeruginosa

-

production is only 1/15 of N-butanoyl homoserine lactone

703201

-

-

ir

hexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-hexanoyl -L-homoserine lactone

Chromobacterium violaceum

-

-

720388

-

-

?

N-butanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-butanoyl-L-homoserine lactone

2 entries

N-decanoyl -[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-decanoyl -L-homoserine lactone

Acinetobacter sp.

-

-

720863

-

-

?

N-hexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-hexanoyl-L-homoserine lactone

2 entries

octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-octanoyl-L-homoserine lactone

2 entries

S-adenosyl-L-methionine + 3-hydroxybutyryl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-hydroxybutyryl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Aliivibrio fischeri

-

substrate of LuxM

665363

-

-

?

S-adenosyl-L-methionine + 3-oxodecanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxodecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

2 entries

S-adenosyl-L-methionine + 3-oxododecanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxododecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Pseudomonas aeruginosa

-

substrate of LasI

666390

-

-

?

S-adenosyl-L-methionine + 3-oxohexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxohexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

5 entries

S-adenosyl-L-methionine + 3-oxooctanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxooctanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

3 entries

S-adenosyl-L-methionine + butyryl-[acyl-carrier protein]

5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein]

3 entries

S-adenosyl-L-methionine + decanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-decanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Burkholderia thailandensis

-

-

663701

-

-

?

S-adenosyl-L-methionine + hexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-hexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

3 entries

S-adenosyl-L-methionine + octanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

3 entries

additional information

?

-

15 entries

3-hydroxydecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-hydroxydecanoyl-L-homoserine lactone

Phaeobacter inhibens

-

-

719734

-

-

?

3-hydroxydecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-hydroxydecanoyl-L-homoserine lactone

Phaeobacter inhibens DSM 17395

-

-

719734

-

-

?

3-oxo-dodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxododecanoyl-L-homoserine lactone

Pseudomonas aeruginosa

-

-

718655

-

-

?

3-oxo-dodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxododecanoyl-L-homoserine lactone

Pseudomonas putida

-

-

718655

-

-

?

3-oxo-dodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxododecanoyl-L-homoserine lactone

Pseudomonas putida WCS358

-

-

718655

-

-

?

3-oxododecanoyl-[acyl carrier protein] + S-adenosyl-L-methionine

N-(3-oxododecanoyl)-homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

Pseudomonas aeruginosa

A9JPX3, A9JPX5

-

701799

-

-

ir

3-oxododecanoyl-[acyl carrier protein] + S-adenosyl-L-methionine

N-(3-oxododecanoyl)-homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

Pseudomonas aeruginosa PUPa3

A9JPX3, A9JPX5

-

701799

-

-

ir

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Aliivibrio fischeri

-

-

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Dickeya chrysanthemi

-

-

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Pantoea stewartii

-

-

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Pectobacterium carotovorum

-

-

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Pseudomonas syringae

-

-

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Serratia marcescens

-

SpnI (like EsaI) synthesizes primarily N-3-oxohexanoyl-L-homoserine lactone

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Serratia marcescens SS-1

-

SpnI (like EsaI) synthesizes primarily N-3-oxohexanoyl-L-homoserine lactone

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Yersinia enterocolitica

-

-

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Yersinia pestis

-

-

720492

-

-

?

3-oxohexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-3-oxohexanoyl-L-homoserine lactone

Yersinia pseudotuberculosis

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Acinetobacter sp.

-

-

720863

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Pectobacterium carotovorum

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Pseudomonas aeruginosa

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Pseudomonas syringae

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Yersinia enterocolitica

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Yersinia pestis

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

an [acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Yersinia pseudotuberculosis

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Acinetobacter baumannii

B0FLN1

-

687413

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Agrobacterium tumefaciens

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Aliivibrio fischeri

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Dickeya chrysanthemi

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Escherichia coli

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Pantoea stewartii

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Serratia marcescens

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Serratia marcescens SS-1

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Serratia sp.

-

-

720492

-

-

?

an acyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone

Serratia sp. 39006

-

-

720492

-

-

?

butanoyl [acyl carrier protein] + S-adenosyl-L-methionine

N-butanoyl homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

Pseudomonas aeruginosa

-

-

703201

-

-

ir

butanoyl [acyl carrier protein] + S-adenosyl-L-methionine

N-butanoyl homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

Pseudomonas aeruginosa

A9JPX3, A9JPX5

-

701799

-

-

ir

butanoyl [acyl carrier protein] + S-adenosyl-L-methionine

N-butanoyl homoserine lactone + [acyl carrier protein] + 5'-methyl-thioadenosine

Pseudomonas aeruginosa PUPa3

A9JPX3, A9JPX5

-

701799

-

-

ir

N-butanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-butanoyl-L-homoserine lactone

Serratia sp.

-

-

720492

-

-

?

N-butanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-butanoyl-L-homoserine lactone

Serratia sp. 39006

-

-

720492

-

-

?

N-hexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-hexanoyl-L-homoserine lactone

Serratia sp.

-

-

720492

-

-

?

N-hexanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-hexanoyl-L-homoserine lactone

Serratia sp. 39006

-

-

720492

-

-

?

octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-octanoyl-L-homoserine lactone

Burkholderia glumae

-

-

720916

-

-

?

octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine

[acyl-carrier protein] + S-methyl-5'-thioadenosine + N-octanoyl-L-homoserine lactone

Burkholderia glumae BGR1

-

-

720916

-

-

?

S-adenosyl-L-methionine + 3-oxodecanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxodecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis

-

substrate of YspI

665410

mass spectrometry product determination

-

?

S-adenosyl-L-methionine + 3-oxodecanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxodecanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis KIM6+

-

substrate of YspI

665410

mass spectrometry product determination

-

?

S-adenosyl-L-methionine + 3-oxohexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxohexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Aliivibrio fischeri

-

-

666767

-

-

?

S-adenosyl-L-methionine + 3-oxohexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxohexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Aliivibrio fischeri

-

substrate of LuxI

665363

-

-

?

S-adenosyl-L-methionine + 3-oxohexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxohexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Pectobacterium carotovorum subsp. carotovorum

Q6R8K9

substrate of wild-type ExpISCC1, specific for

665602

-

-

?

S-adenosyl-L-methionine + 3-oxohexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxohexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis

-

substrate of YspI

665410

mass spectrometry product determination

-

?

S-adenosyl-L-methionine + 3-oxohexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxohexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis KIM6+

-

substrate of YspI

665410

mass spectrometry product determination

-

?

S-adenosyl-L-methionine + 3-oxooctanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxooctanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Pectobacterium carotovorum subsp. carotovorum

Q6R8K9

substrate of wild-type ExpISCC3065, specific for

665602

-

-

?

S-adenosyl-L-methionine + 3-oxooctanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxooctanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis

-

substrate of YspI

665410

mass spectrometry product determination

-

?

S-adenosyl-L-methionine + 3-oxooctanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-3-oxooctanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis KIM6+

-

substrate of YspI

665410

mass spectrometry product determination

-

?

S-adenosyl-L-methionine + butyryl-[acyl-carrier protein]

5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Aeromonas hydrophila

-

substrate of AhyI

664987

-

-

?

S-adenosyl-L-methionine + butyryl-[acyl-carrier protein]

5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Pseudomonas aeruginosa

P54291

-

666383

-

-

?

S-adenosyl-L-methionine + butyryl-[acyl-carrier protein]

5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Pseudomonas aeruginosa

-

substrate of RhlI, synthesis of a quorum-sensing molecule involved in the regulation of many processes involving the bacterial virulence and infectivity

664092

-

-

?

S-adenosyl-L-methionine + hexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-hexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Aliivibrio fischeri

-

-

666767

-

-

?

S-adenosyl-L-methionine + hexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-hexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Burkholderia thailandensis

-

substrate of BtaI1 and BtaI3

663701

-

-

?

S-adenosyl-L-methionine + hexanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-hexanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis

-

substrate of YspI

665410

mass spectrometry product determination

-

?

S-adenosyl-L-methionine + octanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Aliivibrio fischeri

-

substrate of AinS

665363

-

-

?

S-adenosyl-L-methionine + octanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Burkholderia thailandensis

-

substrate of BtaI1 and BtaI3

663701

-

-

?

S-adenosyl-L-methionine + octanoyl-[acyl-carrier protein]

5'-methylthioadenosine + N-octanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

Yersinia pestis

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substrate of YspI

665410

mass spectrometry product determination

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additional information

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Acinetobacter sp.

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five of the clinical isolates produce N-decanoyl homoserine lactone and two isolates produce acyl-homoserine lactone with a chain length equal to C12

720863

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additional information

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Aeromonas hydrophila

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the LuxR homologue AhyR regulates AhyI positively and negatively in a growth phase-dependent manner, regulation overview

664987

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additional information

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Aliivibrio fischeri

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acylhomoserine lactones are autoinducers of quorum-sensing signaling

666767

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additional information

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Burkholderia thailandensis

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AHSs are key enzymes of the quorum-sensing systems of Gram-negative bacteria, the quorum-sensing system of Burkholderia thailandiensis contains at least three AHL synthases and five transcriptional regulators, enzyme disruption mutant strains cause hyper-hemolysis of sheep erythrocytes

663701

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additional information

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Pantoea stewartii

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EsaI and LasI produce N-acyl-L-homoserine lactones signaling molecules as autoinducers of quorum-sensing signaling and regulation of gene expression

665409

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additional information

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Pantoea stewartii subsp. stewartii

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key enzyme of the quorum-sensing signaling pathway

666800

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additional information

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Pseudomonas aeruginosa

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LasI and LasR form a quorum-sensing system playing a pivotal role in virulence gene regulation of the opportunistic human pathogen Pseudomonas aeruginosa

666390

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additional information

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Pseudomonas aeruginosa

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the enzyme is involved in quorum-sensing signaling by synthesizing the signaling molecules which regulates the virulence genes, N-acylhomoserine lactones are autoinducers, the enzyme acts as a quorum-sensing signal generator, mechanism, overview

666769

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additional information

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Pseudomonas aeruginosa

P54291

the enzyme is involved in quorum-sensing signaling by synthesizing the signaling molecules, the autoinducers N-acylhomoserine lactones, the enzyme acts as a quorum-sensing signal generator

666383

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additional information

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Pseudomonas aeruginosa

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the enzyme is involved in quorum-sensing signaling by synthesizing the signaling molecules, the autoinducers N-acylhomoserine lactones, the enzyme acts as a quorum-sensing signal generator

666383

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additional information

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Pseudomonas aeruginosa PAO-JP1

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the enzyme is involved in quorum-sensing signaling by synthesizing the signaling molecules which regulates the virulence genes, N-acylhomoserine lactones are autoinducers, the enzyme acts as a quorum-sensing signal generator, mechanism, overview

666769

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additional information

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Serratia sp.

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SmaI synthesizes predominantly butanoyl-HSL and smaller amounts of hexanoyl-HSL

720492

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additional information

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Serratia sp. 39006

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SmaI synthesizes predominantly butanoyl-HSL and smaller amounts of hexanoyl-HSL

720492

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additional information

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Yersinia pestis

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substrate specificities of native strain KIM6+ enzyme and recombinant YspI expressed in Escherichia coli strain BL21(DE3), the recombinant enzyme shows a similar substrate profile as the native enzyme, overview

665410

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additional information

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Yersinia pestis KIM6+

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substrate specificities of native strain KIM6+ enzyme and recombinant YspI expressed in Escherichia coli strain BL21(DE3), the recombinant enzyme shows a similar substrate profile as the native enzyme, overview

665410

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