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2.3.1.176: propanoyl-CoA C-acyltransferase

This is an abbreviated version!
For detailed information about propanoyl-CoA C-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.176

Reaction

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA
+
propanoyl-CoA
=
CoA
+
3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA

Synonyms

3-oxopristanoyl-CoA hydrolase, 3-oxopristanoyl-CoA thiolase, EC 2.3.1.154, HaSCP-2, MsSCP-x/SCP-2 protein, non-specific lipid transfer protein, nsLTP, oxopristanoyl-CoA thiolase, peroxisomal 3-oxoacyl coenzyme A thiolase, peroxisomal thiolase 2, peroxisome sterol carrier protein thiolase, propanoyl-CoA C-acyltransferase, PTE-2, SCP-2, SCP-2/thiolase, SCP-x, Scp2, SCP2L2, SCPc, SCPx, sterol carrier protein 2-like 2, sterol carrier protein 2/3-oxoacyl-CoA thiolase, sterol carrier protein type 2, sterol carrier protein x, sterol carrier protein-2, sterol carrier protein-c, sterol carrier protein-x, sterol carrier protein-x/sterol carrier protein-2, TgSCP2, UMAG_11938

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.176 propanoyl-CoA C-acyltransferase

Reference

Reference on EC 2.3.1.176 - propanoyl-CoA C-acyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Pedersen, J.I.; Gustafsson, J.
Conversion of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoic acid into cholic acid by rat liver peroxisomes
FEBS Lett.
121
345-348
1980
Rattus norvegicus
Manually annotated by BRENDA team
Falany, C.N.; Johnson, M.R.; Barnes, S.; Diasio, R.B.
Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase
J. Biol. Chem.
269
19375-19379
1994
Homo sapiens
Manually annotated by BRENDA team
Kase, F.; Bjorkhem, I.; Pedersen, J.I.
Formation of cholic acid from 3alpha,7alpha,12alpha-trihydroxy-5 beta-cholestanoic acid by rat liver peroxisomes
J. Lipid Res.
24
1560-1567
1983
Rattus norvegicus
Manually annotated by BRENDA team
Schroeder, F.; Atshaves, B.P.; McIntosh, A.L.; Gallegos, A.M.; Storey, S.M.; Parr, R.D.; Jefferson, J.R.; Ball, J.M.; Kier, A.B.
Sterol carrier protein-2: new roles in regulating lipid rafts and signaling
Biochim. Biophys. Acta
1771
700-718
2007
Mus musculus
Manually annotated by BRENDA team
Martin, G.G.; Hostetler, H.A.; McIntosh, A.L.; Tichy, S.E.; Williams, B.J.; Russell, D.H.; Berg, J.M.; Spencer, T.A.; Ball, J.; Kier, A.B.; Schroeder, F.
Structure and function of the sterol carrier protein-2 N-terminal presequence
Biochemistry
47
5915-5934
2008
Homo sapiens (P22307)
Manually annotated by BRENDA team
Guo, X.; Zheng, S.; Liu, L.; Feng, Q.
The sterol carrier protein 2/3-oxoacyl-CoA thiolase (SCPx) is involved in cholesterol uptake in the midgut of Spodoptera litura: Gene cloning, expression, localization and functional analyses
BMC Mol. Biol.
10
102
2009
Spodoptera litura (D1GJ60), Spodoptera litura
Manually annotated by BRENDA team
Atshaves, B.P.; McIntosh, A.L.; Martin, G.G.; Landrock, D.; Payne, H.R.; Bhuvanendran, S.; Landrock, K.K.; Lyuksyutova, O.I.; Johnson, J.D.; Macfarlane, R.D.; Kier, A.B.; Schroeder, F.
Overexpression of sterol carrier protein-2 differentially alters hepatic cholesterol accumulation in cholesterol-fed mice
J. Lipid Res.
50
1429-1447
2009
Mus musculus (P32020), Mus musculus
Manually annotated by BRENDA team
McIntosh, A.L.; Atshaves, B.P.; Gallegos, A.M.; Storey, S.M.; Reibenspies, J.H.; Kier, A.B.; Meyer, E.; Schroeder, F.
Structure of dehydroergosterol monohydrate and interaction with sterol carrier protein-2
Lipids
43
1165-1184
2008
Homo sapiens (P22307)
Manually annotated by BRENDA team
Kim, M.S.; Lan, Q.
Sterol carrier protein-x gene and effects of sterol carrier protein-2 inhibitors on lipid uptake in Manduca sexta
BMC Physiol.
10
9
2010
Manduca sexta (D8VD26), Manduca sexta (D8VD27), Manduca sexta
Manually annotated by BRENDA team
Du, X.; Ma, H.; Zhang, X.; Liu, K.; Peng, J.; Lan, Q.; Hong, H.
Characterization of the sterol carrier protein-x/sterol carrier protein-2 gene in the cotton bollworm, Helicoverpa armigera
J. Insect Physiol.
58
1413-1423
2012
Helicoverpa armigera (K7NSY9), Helicoverpa armigera
Manually annotated by BRENDA team
Cheng, Z.; Li, Y.; Sui, C.; Sun, X.; Xie, Y.
Synthesis, purification and crystallographic studies of the C-terminal sterol carrier protein type 2 (SCP-2) domain of human hydroxysteroid dehydrogenase-like protein 2
Acta Crystallogr. Sect. F
71
901-905
2015
Homo sapiens (P22307), Homo sapiens
Manually annotated by BRENDA team
Cerqueira, D.; Tran, U.; Romaker, D.; Abreu, J.; Wessely, O.
Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts
Dev. Biol.
394
54-64
2014
Xenopus laevis
Manually annotated by BRENDA team
Fu, Q.; Inankur, B.; Yin, J.; Striker, R.; Lan, Q.
Sterol carrier protein 2, a critical host factor for dengue virus infection, alters the cholesterol distribution in mosquito Aag2 cells
J. Med. Entomol.
52
1124-1134
2015
Aedes aegypti (Q86PR3), Aedes aegypti
Manually annotated by BRENDA team
Liedhegner, E.S.; Vogt, C.D.; Sem, D.S.; Cunningham, C.W.; Hillard, C.J.
Sterol carrier protein-2: binding protein for endocannabinoids
Mol. Neurobiol.
50
149-158
2014
Homo sapiens
Manually annotated by BRENDA team
Ma, H.; Ma, Y.; Liu, X.; Dyer, D.; Xu, P.; Liu, K.; Lan, Q.; Hong, H.; Peng, J.; Peng, R.
NMR structure and function of Helicoverpa armigera sterol carrier protein-2, an important insecticidal target from the cotton bollworm
Sci. Rep.
5
18186
2015
Helicoverpa armigera (K7NSY9), Helicoverpa armigera
Manually annotated by BRENDA team
Singarapu, K.K.; Ahuja, A.; Potula, P.R.; Ummanni, R.
Solution nuclear magnetic resonance studies of sterol carrier protein 2 like 2 (SCP2L2) reveal the insecticide specific structural characteristics of SCP2 proteins in Aedes aegypti mosquitoes
Biochemistry
55
4919-4927
2016
Aedes aegypti (Q0GY13), Aedes aegypti
Manually annotated by BRENDA team
Fu, Y.; Cui, X.; Liu, J.; Zhang, X.; Zhang, H.; Yang, C.; Liu, Q.
Synergistic roles of acyl-CoA binding protein (ACBP1) and sterol carrier protein 2 (SCP2) in Toxoplasma lipid metabolism
Cell. Microbiol.
21
e12970
2019
Toxoplasma gondii
Manually annotated by BRENDA team
Cai, J.; Du, X.; Wang, C.; Lin, J.; Du, X.
Identification of potential Helicoverpa armigera (Lepidoptera Noctuidae) sterol carrier protein-2 inhibitors through high-throughput virtual screening
J. Econ. Entomol.
110
1779-1784
2017
Helicoverpa armigera (K7NSY9), Helicoverpa armigera
Manually annotated by BRENDA team
Krombach, S.; Reissmann, S.; Kreibich, S.; Bochen, F.; Kahmann, R.
Virulence function of the Ustilago maydis sterol carrier protein 2
New Phytol.
220
553-566
2018
Ustilago maydis (A0A0D1E3D1)
Manually annotated by BRENDA team
Li, N.C.; Fan, J.; Papadopoulos, V.
Sterol carrier protein-2, a nonspecific lipid-transfer protein, in intracellular cholesterol trafficking in testicular Leydig cells
PLoS ONE
11
e0149728
2016
Mus musculus (P32020), Mus musculus
Manually annotated by BRENDA team