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2.3.1.176: propanoyl-CoA C-acyltransferase

This is an abbreviated version!
For detailed information about propanoyl-CoA C-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.176

Reaction

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA
+
propanoyl-CoA
=
CoA
+
3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA

Synonyms

3-oxopristanoyl-CoA hydrolase, 3-oxopristanoyl-CoA thiolase, EC 2.3.1.154, HaSCP-2, MsSCP-x/SCP-2 protein, non-specific lipid transfer protein, nsLTP, oxopristanoyl-CoA thiolase, peroxisomal 3-oxoacyl coenzyme A thiolase, peroxisomal thiolase 2, peroxisome sterol carrier protein thiolase, propanoyl-CoA C-acyltransferase, PTE-2, SCP-2, SCP-2/thiolase, SCP-x, Scp2, SCP2L2, SCPc, SCPx, sterol carrier protein 2-like 2, sterol carrier protein 2/3-oxoacyl-CoA thiolase, sterol carrier protein type 2, sterol carrier protein x, sterol carrier protein-2, sterol carrier protein-c, sterol carrier protein-x, sterol carrier protein-x/sterol carrier protein-2, TgSCP2, UMAG_11938

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.176 propanoyl-CoA C-acyltransferase

Inhibitors

Inhibitors on EC 2.3.1.176 - propanoyl-CoA C-acyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-diphenyl-4H,4'H-[6,6'-bibenzo[d][1,3]oxazine]-4,4'-dione
sterol carrier protein-2 is a validated target for development of novel insecticides due to its divergent protein structure and function from the vertebrate SCP-2. HaSCP-2 is important for normal development and fertility in Helicoverpa armigera. H1 (N2,N7-di(1-naphthyl)-9H-2,7-fluorenedisulfonamide) and H14 (2,2'-diphenyl-4H,4'H-[6,6'-bibenzo[d][1,3]oxazine]-4,4'-dione) have inhibitory effect on the growth of Helicoverpa armigera larvae
alpha-mangostin
SCPI-1 or mangostin-treatment cause most death on day-3 and day-4 after the treatment started when larvae in control groups were all alive and molting from 1st to 2nd instars
N-(4-{[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]amino}phenyl)acetamide
i.e. SCPI-1, SCPI-1 or mangostin-treatment cause most death on day-3 and day-4 after the treatment started when larvae in control groups were all alive and molting from 1st to 2nd instars
N2,N7-di(1-naphthyl)-9H-2,7-fluorenedisulfonamide
sterol carrier protein-2 is a validated target for development of novel insecticides due to its divergent protein structure and function from the vertebrate SCP-2. HaSCP-2 is important for normal development and fertility in Helicoverpa armigera. H1 (N2,N7-di(1-naphthyl)-9H-2,7-fluorenedisulfonamide) and H14 (2,2'-diphenyl-4H,4'H-[6,6'-bibenzo[d][1,3]oxazine]-4,4'-dione) have inhibitory effect on the growth of Helicoverpa armigera larvae
SCPI-1
i.e. N-(4-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]amino]phenyl)acetamide hydrobromide