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2.3.1.176: propanoyl-CoA C-acyltransferase

This is an abbreviated version!
For detailed information about propanoyl-CoA C-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.176

Reaction

3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA
+
propanoyl-CoA
=
CoA
+
3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA

Synonyms

3-oxopristanoyl-CoA hydrolase, 3-oxopristanoyl-CoA thiolase, EC 2.3.1.154, HaSCP-2, MsSCP-x/SCP-2 protein, non-specific lipid transfer protein, nsLTP, oxopristanoyl-CoA thiolase, peroxisomal 3-oxoacyl coenzyme A thiolase, peroxisomal thiolase 2, peroxisome sterol carrier protein thiolase, propanoyl-CoA C-acyltransferase, PTE-2, SCP-2, SCP-2/thiolase, SCP-x, Scp2, SCP2L2, SCPc, SCPx, sterol carrier protein 2-like 2, sterol carrier protein 2/3-oxoacyl-CoA thiolase, sterol carrier protein type 2, sterol carrier protein x, sterol carrier protein-2, sterol carrier protein-c, sterol carrier protein-x, sterol carrier protein-x/sterol carrier protein-2, TgSCP2, UMAG_11938

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.176 propanoyl-CoA C-acyltransferase

Engineering

Engineering on EC 2.3.1.176 - propanoyl-CoA C-acyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
F110W
reduced ability to bind with cholesterol
F53A
reduced ability to bind with cholesterol
F53W
strongly reduced ability to bind with cholesterol
F89A
reduced ability to bind with cholesterol
I117M
reduced ability to bind with cholesterol
Q131A
reduced ability to bind with cholesterol
Y51A
reduced ability to bind with cholesterol
Y51W
reduced ability to bind with cholesterol
additional information